Jile Xin

ORCID: 0009-0006-8545-0191
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Research Areas
  • Soil Mechanics and Vehicle Dynamics
  • Medicinal Plant Pharmacodynamics Research
  • Traditional Chinese Medicine Analysis
  • Animal Behavior and Welfare Studies
  • Cardiac Fibrosis and Remodeling
  • Business Process Modeling and Analysis
  • Protein purification and stability
  • Regulation of Appetite and Obesity
  • Phytoestrogen effects and research
  • Flavonoids in Medical Research
  • Nanoparticle-Based Drug Delivery
  • Cardiovascular Effects of Exercise
  • Biological Activity of Diterpenoids and Biflavonoids
  • Cavitation Phenomena in Pumps
  • Structural Health Monitoring Techniques
  • Wind Energy Research and Development
  • Food Supply Chain Traceability
  • Advanced Chemical Sensor Technologies
  • Turbomachinery Performance and Optimization
  • Insect Utilization and Effects
  • Pharmacology and Obesity Treatment
  • Tryptophan and brain disorders
  • Drug Transport and Resistance Mechanisms
  • Bone Metabolism and Diseases
  • Endoplasmic Reticulum Stress and Disease

First Affiliated Hospital of Henan University
2020-2024

Inner Mongolia University
2023

Jilin University
2013-2017

Dalian Medical University
2010-2013

Second Affiliated Hospital of Dalian Medical University
2010-2013

Jilin Medical University
2013

Beijing Technology and Business University
2010

Natural product Tanshinone IIA (TanIIA) induces apoptosis and differentiation in hepatocellular carcinoma (HCC) cells, but its clinical use is limited due to poor water solubility lack of appropriate formulations for drug delivery. In this study, we capsulated TanIIA into a microemulsion (ME) that was composed phospholipid, ethyl oleate, glycerol pluronic F68. We then determined the anticancer effects mechanisms action ME with vitro vivo HCC models. The mRNA protein levels apoptosis-related...

10.1142/s0192415x13500146 article EN The American Journal of Chinese Medicine 2013-01-01

The aim of the present study was to examine protective effects and mechanism sika deer (Cervus nippon Temminck) velvet antler polypeptides (VAPs) against MPP+ exposure in SH‑SY5Y human neuroblastoma cell line. cytotoxicity VAPs on cells were determined using an MTT assay. Cell apoptosis mitochondrial membrane potential detected Hoechst 33342 Rhodamine123 staining, respectively. Endoplasmic reticulum (ER) stress‑related reactive oxygen species (ROS) production 2',7'‑dichlorodihydrofluorescein...

10.3892/mmr.2017.7303 article EN cc-by-nc-nd Molecular Medicine Reports 2017-08-21

The natural product tanshinone (Tan) induces apoptosis and differentiation in hepatocellular carcinoma (HCC) cells, but its clinical use is limited by poor water solubility the lack of appropriate formulations. In this study, Tan was encapsulated into a microemulsion (ME) composed phospholipid, ethyl oleate, glycerol Pluronic F68. anticancer effects mechanisms action ME were tested using vitro vivo HCC models. mRNA protein levels related molecules (Bcl-2 Bax) analyzed H22 murine hepatoma...

10.3892/mmr.2012.1129 article EN Molecular Medicine Reports 2012-10-12

Abstract Dilated cardiomyopathy (DCM) is a common cause of heart failure, and males are more likely to suffer from DCM than females. This research aimed at exploring possible DCM-associated genes their latent regulatory effects in female male patients. WGCNA analysis found that the yellow module, 341 367 key DEGs were identified females males, respectively. A total 22 hub 17 PPI networks based on Metascape database. And twelve eight potential TFs also Eight miRNAs 15 screened both which may...

10.1038/s41598-023-36117-0 article EN cc-by Scientific Reports 2023-06-02

Rehmannia glutinosa, a valuable medicinal plant, is threatened by ring rot, condition that greatly affects its yield and quality. Interactions between plant the rhizosphere soil microbiome in context of pathogen invasion are generally more specific, with recruitment specialized microbes potentially antagonistic to certain pathogen. Isolation microorganisms from healthy rot-infected R. glutinosa was carried out screen antifungal microbes. A strain designated RerS4 isolated strong activities...

10.1016/j.heliyon.2023.e19543 article EN cc-by-nc-nd Heliyon 2023-08-28

Cognitive impairment (CI) refers to dysfunctional cognition, which encompasses a spectrum of disorders, ranging from mild cognitive dementia. Any factor that results in cortical damage may cause CI. Total flavonoids Selaginella pulvinata (TFSP), have shown promising antioxidant and protective effects animal models. In the present study, mice were intraperitoneally treated with scopolamine, sodium nitrite or 45% ethanol induce memory impairment, assessed using step-down test. After performing...

10.3892/br.2020.1315 article EN Biomedical Reports 2020-06-09

In response to the complex animal husbandry environment, wide livestock range, and labor shortage in Inner Mongolia grasslands, this study designed an intelligent control system for robotic vehicles used natural grazing grassland environments. The consists of software hardware components motion algorithms. Based on application characteristics different mechanisms vehicle, vehicle is decomposed into longitudinal speed lateral steering control. adopts traditional...

10.3390/electronics12143078 article EN Electronics 2023-07-14

In order to achieve goat localization help prevent goats from wandering, we proposed an efficient target method based on machine vision. Albas velvet a farm in Ertok Banner, Ordos City, Inner Mongolia Autonomous Region, China, were the main objects of study. First, detecting using shallow convolutional neural network, ShallowSE, with channel attention mechanism SENet, GeLU activation function and layer normalization. Second, designed three fully connected coordinate regression network models...

10.3390/ani13203242 article EN cc-by Animals 2023-10-18

Background: Si-Ni-San (SNS) is the formula prescription of Traditional Chinese Medicine (TCM) with anti-depression properties, but its underlying mechanisms remain unclear. Objective: This study provides novel approaches for and offers new opportunities exploring pharmacological properties SNS. Methods: The ingredients in SNS implicated treatment depression were identified studied using network pharmacology. SwissTargetPrediction molecular docking used to interaction their targets....

10.2174/0115734099305381240613114436 article EN Current Computer - Aided Drug Design 2024-08-12

Aiming at the problem of time-consuming, labor-intensive, and low-accuracy monitoring goat motion behavior (lying, standing, walking, running) while relying on three-axis acceleration sensor taking data obtained from back collection point as research object, a method based social learning (SL) is proposed using Whale Optimization Algorithm (WOA) XGBoost for recognition. In this method, parameters are optimized by WOA combined with strategies to improve classification recognition accuracy....

10.3390/electronics12163506 article EN Electronics 2023-08-18

Automatic control on business process with workflow is the core part of a project management system. A process-oriented system model which can support configuration, control, task assignment, submitting and approval, cooperative work presented. The hierachical architecture that consists three layers, i.e. database layer, engine user interface layer. It based Browser/Server provide multi-user, distributed access properties. XPDL relational technologies work, branch selection configuration....

10.1109/cscwd.2010.5471976 article EN 2010-04-01

To investigate the regulation of Cha Gan Beng Ga on activity biomarker PGC-1α in vivo and vitro, lay foundation for studying efficacy result xenograft tumor model extracting active constituents.(1) The coarse powder was extracted with 70% ethanol solution through heating refluxing, finally used to freeze dry powder. (2) 50 mg x kg(-1) freeze-dried power orally administrated KM C57BL/6J mice once daily, lasting 5 consecutive days; different concentrations materials given non-small cell lung...

10.4268/cjcmm20141733 article EN China Journal of Chinese Materia Medica 2014-09-01

This paper proposes a design method for channel-type sheep dynamic weighing system to address the current problems encountered by pastoralists at home and abroad, such as time-consuming weighing, difficulties with data collection, management of stress response in sheep. The complete includes hardware structure, characteristics, Kalman-aggregate empirical modal decomposition algorithm (Kalman-EEMD algorithm) model processing. noise suppression effects Kalman filter, (EMD), ensemble (EEMD)...

10.3390/electronics12071715 article EN Electronics 2023-04-04
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