- Wound Healing and Treatments
- Heat shock proteins research
- Electrospun Nanofibers in Biomedical Applications
- Circular RNAs in diseases
- Antimicrobial Peptides and Activities
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Surgical Sutures and Adhesives
- Galectins and Cancer Biology
- Planarian Biology and Electrostimulation
- Skin Protection and Aging
- Burn Injury Management and Outcomes
- Silk-based biomaterials and applications
- Periodontal Regeneration and Treatments
- Hemostasis and retained surgical items
- Phytochemical compounds biological activities
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Endoplasmic Reticulum Stress and Disease
- Beetle Biology and Toxicology Studies
- RNA modifications and cancer
- Genital Health and Disease
- RNA Research and Splicing
Ningxia Medical University
2025
Wuhan University of Science and Technology
2025
Southern Medical University
2022-2024
Nanfang Hospital
2022-2024
Yuncheng University
2024
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2024
Improper management of diabetic wound effusion and disruption the endogenous electric field can lead to passive healing damaged tissue, affecting process tissue cascade repair. This study developed an extracellular matrix sponge scaffold (K1P6@Mxene) by incorporating Mxene into acellular dermal stroma-hydroxypropyl chitosan interpenetrating network structure. is designed couple with promote precise remodelling in wounds. The fibrous structure closely resembles that a natural matrix,...
Background: Atherosclerosis (AS), with a profound inflammatory response, is the basis of cardiovascular diseases. Previous reports showed that heat shock protein family B member 1 (HSPB1) has protective effect against AS, but specific mechanism still unclear. In this study, we aim to explore functions and downstream targets HSPB1 in human umbilical vein endothelial cells (HUVECs). Methods: Expression gene was knocked down HUVECs. Cellular phenotype then assessed transcriptome data (RNA-seq)...
In recent years, the role of circular RNA in cancer cells has been studied broadly; however, functional significance regulation tumor microenvironment (TME) is not fully understood. this study, we aimed to reveal circ_TNFRSF21 M2 macrophage-induced cutaneous squamous cell carcinoma (cSCC) angiogenesis. Quantitative polymerase chain reaction and Western blotting were performed determine levels indicated genes. Direct binding between miR-3619-5p, ROCK2 was verified by dual-luciferase activity....
Cantharidin (CTD) as a treatment for primary liver cancer are well known, and although structural alteration nano-delivery efficient in diminishing toxicity, its urinary digestive toxicity has hindered clinical application. Based on the synergistic effect of CTD baicalin (BA) proliferation inhibition tumor cells, highly expressed folic acid (FA) receptor cell membrane high negative potential mitochondria, we synthesized CHEMS-FRFK prepared dual-ligand modified co-delivery liposomes...
Abstract Background: Cutaneous squamous cell carcinoma (cSCC) is a malignant proliferation of cutaneous epithelium. Ferroptosis new type death involved in cancer progression. M2 macrophage derived exosomes promote and We intended to investigate the role macrophages on ferroptosis cSCC explore underlying mechanism. Methods: samples adjacent normal tissues were obtained from patients. Exosomes isolated differentiated human mononuclear (THP-1) cells by flow cytometry. Cell viability, iron...
Abstract Background Although acellular dermal matrix (ADM) and concentrated growth factor (CGF) are both used in regenerative medicine, CGF has been hampered by problems such as burst release, ADM is only an outer dressing for wound healing. In this study, we aim to prepare composite scaffolds (CADMS-G-2-Hep) with good NIR photothermal response, antibacterial activity, drug delivery ability introducing polydopamine nanoparticles (PDA NPS) excellent conversion into chitosan (CS)...
Although acellular dermal matrix (ADM) and concentrated growth factor (CGF) are used in regenerative medicine, CGF has been hampered by problems such as burst release, ADM is only an outer dressing for wound healing. In this study, we aim to prepare composite scaffolds (CADMS-G-2-Hep) with good NIR photothermal response, antibacterial activity, drug delivery ability introducing polydopamine nanoparticles (PDA NPS) excellent conversion into chitosan (CS) interpenetrating network structure...