- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- HIV Research and Treatment
- Palliative Care and End-of-Life Issues
- Pain Management and Opioid Use
- HIV/AIDS drug development and treatment
- Business and Management Studies
- EFL/ESL Teaching and Learning
- Male Reproductive Health Studies
- Linguistics and Education Research
- Metabolism, Diabetes, and Cancer
- Cardiovascular Health and Disease Prevention
- Parvovirus B19 Infection Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Palliative and Oncologic Care
- Diabetes Treatment and Management
- Blood properties and coagulation
- Environmental and biological studies
- Liver Disease Diagnosis and Treatment
- Pediatric Pain Management Techniques
- Patient Dignity and Privacy
- Medical Education and Admissions
- Herpesvirus Infections and Treatments
- Dialysis and Renal Disease Management
Centro Hospitalar de Lisboa Ocidental
2012-2024
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2024
Hospital Braga
2024
Centro Hospitalar do Tâmega e Sousa
2024
Centro Hospitalar de Lisboa Central
2024
Hospital de Egas Moniz
2019
Polytechnic Institute of Coimbra
2016
Universidade Estadual de Campinas (UNICAMP)
2016
Instituto Superior de Contabilidade e Administração de Coimbra
2016
Universidade do Estado do Rio de Janeiro
1999-2004
Background: Hemoglobinopathies are the most common group of genetic disorders worldwide.They mainly result from autosomal recessive transmission mutated genes behind synthesis globin chains, and fall into two main groups: thalassemia syndromes, structural haemoglobin (Hb) variants.Although some Hb variants silent in heterozygotes, they can be severe homozygous forms.Aim: To analyse incidence hemoglobinopathies all samples studied both for guided screening incidental finding, last 5 years to...
Background: Rhabdomyoma is the most common cardiac tumor in fetal life. It has frequent association with tuberous sclerosis complex and may lead to heart failure, a potentially fatal condition. The use of transplacental sirolimus, mTOR inhibitor, emerged as novel treatment symptomatic rhabdomyomas, there are, though, only few cases described. Case Presentation: A 37-years old at 29 weeks 4 days had diagnosis tumor, adhered adjacent left ventricle, associated dysfunction polyhydramnios....
To characterize the HIV-2 integrase gene polymorphisms and pathways to resistance of patients failing a raltegravir-containing regimen, we studied 63 strand transfer inhibitors (INSTI)-naïve patients, 10 heavily pretreated exhibiting virological failure while receiving salvage regimen. All were infected by group A. 61.4% residues conserved, including catalytic motif residues. No INSTI-major mutations detected in virus population from naïve but two amino acids that are secondary INSTIs HIV-1...
Objectives: To evaluate the level of anxiety experienced by 1st and 5th-year dental students in Portugal. Methods: The target population was from Portuguese universities attending 5th years school during academic year 2022/2023. Data were collected using previously validated Modified Dental Anxiety Scale, available online on Google Forms platform between February 2023 June 2023. statistically analyzed IBM SPSS Statistics version 29, descriptive inferential analysis methods. Mann-Whitney...
Para avaliar a resposta inflamatória, representada pelas proteínas de fase aguda, estudamos 48 pacientes com diabetes tipo 1 (DM1) sem complicações [23F:25M; 19,9±9,8 anos e 5 (1-21) duração da doença& 66 indivíduos DM, pareados quanto ao sexo, idade estadiamento puberal (critérios Tanner). Foram dosadas proteína C reativa (PCR), alfa1-glicoproteína ácida (alfa-1GPA) fibrinogênio, por imuno-turbidimetria. A taxa excreção albumina (EUA) foi determinada RIE, em amostra urina 10h,...
Of the 21 Portuguese teams identified, 10 accepted to participate in study. A total of 164 patients were included with a median 15.5 per team (4-32). all included, 60 (37%) identified as inpatients palliative care units; 59 (36%) by an intrahospital support team; 26 (16%) outpatients; and 19 (12%) at home. The age was 71 years (16-95). Fifty-one percent females. diagnosis cancer 151 (92%) patients. most common colorectal 22 (15%) patients, followed gastric 17 (11%), head neck breast 15...
Objective: To study the burden of patients’ symptoms other than pain and their treatment by Portuguese palliative care teams. Methods: Of 21 teams identified, 10 accepted to participate. Data from all patients observed on 18th week 2011 were collected. Results: One hundred sixty-four included in this study. fifty-one (92%) had cancer. The median age was 71 years (16-95) 84 (51%) females. main fatigue (116 [85%]) depression/sadness (107 [65%]). Many different drugs used for symptom control...
To determine the frequency of coronary artery disease, microalbuminuria and relation to lipid profile disorders, blood pressure clinical metabolic features.Fifty-five type 2 diabetic patients (32 females, 23 males), aged 59.9 +/- 9 years with known diabetes duration 11 7.3 were studied. Coronary disease (CAD) was defined as a positive history myocardial infarction, typical angina, revascularization or stress testing. Microalbuminuria when two out three overnight urine samples had urinary...
To assess the association between microalbuminuria with ambulatory blood pressure monitoring in normotensive individuals insulin-dependent diabetes mellitus.Thirty-seven patients underwent determination of rate urinary excretion albumin through radioimmunoassay and monitoring. Their mean age was 26.5+/-6.7 years, duration their disease 8 (1-34) years. Microalbuminuria defined as > or =20 <200 microg/min at least 2 out 3 urine samples.Nine (24.3%) were microalbuminuric. Ambulatory...
Para avaliar a freqüência da microalbuminúria e fatores clínicos metabólicos associados, estudamos 72 pacientes com diabetes tipo 1 [DM1, 38F/34M, sendo 6 crianças, 17 adolescentes 49 adultos, 22,7±9,5 anos 7 (0,1-37,5) de duração doença]. A taxa excreção albumina (EUA) foi determinada em amostra noturna urina 10h. Microalbuminúria definida como EUA > ou = 20 <200mig/min pelo menos 2 3 amostras urina, 25% mostraram-se microalbuminúricos (16 adultos adolescentes) tinham maiores médias...
O exame de urina e um processo analitico que permite identificar os aspectos fisicos, quimicos tambem aos componentes presentes no sedimento urinario. Atraves destas analises podem ser observados avaliados disturbios hemorragicos glomerulares, hepatopatias, erros inatos metabolismo infeccoes urinarias. Desde primordios da civilizacao, a analise considerada importante parâmetro para avaliar homeostase do organismo. fisico podemos observar coloracao, aspecto realizar uma correlacao clinica com...
Urinalise e o exame da urina atraves de um conjunto analises fisicas, quimicas microscopicas, realizado em todos os laboratorios com demanda crescente. Este estudo teve por objetivo ampliar controle qualidade identificacao mudancas no perfil seus resultados. Foram avaliadas retrospectivamente 1702 amostras encaminhadas para realizacao rotina (analise fisico-quimica - Urisys® Roche analise microscopica do sedimento). As alteracoes foram tabuladas as frequencias calculadas. mais frequentes...
Introduction: Cytomegalovirus (CMV) remains a major cause of morbidity and mortality among solid organ transplant recipients, despite remarkable advances in its diagnosis, prevention treatment [1 Dioverti MV, Razonable RR. Clinical utility cytomegalovirus viral load recipients. Curr Opin Infect Dis. 2015;28(4):317–322.[Crossref], [PubMed], [Web Science ®] , [Google Scholar]]. The two methods that are currently used to monitor CMV infection disease these patients the pp65 antigenemia assay...