A5043808379- Breast Implant and Reconstruction
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- AI in cancer detection
- Reconstructive Surgery and Microvascular Techniques
- Surgical Simulation and Training
- Augmented Reality Applications
- 3D Shape Modeling and Analysis
- Neuroendocrine Tumor Research Advances
- Digital Radiography and Breast Imaging
- COVID-19 and healthcare impacts
- Medical Imaging Techniques and Applications
- Neuroblastoma Research and Treatments
- Medical Image Segmentation Techniques
- Anatomy and Medical Technology
- Global Cancer Incidence and Screening
- Lung Cancer Research Studies
- Head and Neck Cancer Studies
- Cancer Treatment and Pharmacology
- Artificial Intelligence in Healthcare and Education
- Venous Thromboembolism Diagnosis and Management
- Nonmelanoma Skin Cancer Studies
- Cardiac tumors and thrombi
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
Champalimaud Foundation
2015-2025
Hospital Dr. Nélio Mendonça
2019-2025
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2024
Centro Hospitalar de Lisboa Ocidental
2024
Hospital Braga
2024
Centro Hospitalar do Tâmega e Sousa
2024
Centro Hospitalar de Lisboa Central
2024
University of Lisbon
2003-2024
Universidade do Porto
2023
INESC TEC
2015
Demand for nipple- and skin- sparing mastectomy (NSM/SSM) with immediate breast reconstruction (BR) has increased at the same time as indications post-mastectomy radiation therapy (PMRT) have broadened. The aim of Oncoplastic Breast Consortium initiative was to address relevant questions arising this clinically challenging scenario.A large global panel oncologic, oncoplastic reconstructive surgeons, patient advocates oncologists developed recommendations clinical practice in an iterative...
Background From the perspective of health care professionals, coronavirus disease (COVID-19) brings many challenges as well opportunities for digital care. One challenge is that professionals are at high risk infection themselves. Therefore, in-person visits need to be reduced an absolute minimum. Connected solutions, including telehealth, remote patient monitoring, and secure communications between clinicians their patients, may rapidly become first choice in such public emergencies....
Introduction: Innovations in 3D spatial technology and augmented reality imaging driven by digital high-tech industrial science have accelerated experimental advances breast cancer the development of medical procedures aimed to reduce invasiveness. Presentation case: A 57-year-old post-menopausal woman presented with screen-detected left-sided cancer. After undergoing all staging pre-operative studies patient was proposed for conservative surgery tumor localization. During surgery, an...
Breast cancer therapy improved significantly, allowing for different surgical approaches the same disease stage, therefore offering patients aesthetic outcomes with similar locoregional control. The purpose of CINDERELLA trial is to evaluate an artificial-intelligence (AI) cloud-based platform (CINDERELLA platform) vs standard approach patient education prior therapy.A prospective randomized international multicentre comparing two methods therapy. After institutional ethics approval and a...
Background: Hemoglobinopathies are the most common group of genetic disorders worldwide.They mainly result from autosomal recessive transmission mutated genes behind synthesis globin chains, and fall into two main groups: thalassemia syndromes, structural haemoglobin (Hb) variants.Although some Hb variants silent in heterozygotes, they can be severe homozygous forms.Aim: To analyse incidence hemoglobinopathies all samples studied both for guided screening incidental finding, last 5 years to...
The deep inferior epigastric perforator (DIEP) is the most commonly used free flap in mastectomy reconstruction.Preoperative imaging techniques are routinely to detect location, diameter and course of perforators, with direct intervention from team, who subsequently draw a chart that will help surgeons choosing best vascular support for reconstruction.In this work, feasibility using computer software preoperative planning 40 patients proposed breast reconstruction DIEP evaluated first time....
Introduction: Augmented reality (AR) has demonstrated a potentially wide range of benefits and educational applications in the virtual health ecosystem. The concept real-time data acquisition, machine learning-aided processing, visualization is foreseen ambition to leverage AR healthcare sector. This breakthrough with immersive technologies like AR, mixed reality, or extended will hopefully initiate new surgical era: that use so-called metaverse. Methods: paper focuses on future breast...
Background: The lateral intercostal artery perforator flap, first described by Hamdi et al as a partial replacement technique for breast-conserving surgery (BCS), was traditionally fasciocutaneous flap with the inherent skin scar on chest wall. Trying to limit donor site morbidity, we further modified original harvesting tissue same without paddle, associated scar, and need reposition patient operating table. Methods: We retrospectively analyzed 52 patients who underwent breast after BCS...
Chemotherapy remains the mainstay in most high-risk breast cancer (BC) settings, with several equivalent options of treatment. However, efficacy each treatment varies between patients and there is currently no test to determine which option will be effective for individual patient. Here, we developed a fast in-vivo BC therapy screening: zebrafish patient-derived-xenograft model (zAvatars), where results can obtained just 10 days. To predictive value zAvatars performed preclinical study, were...
Breast cancer, the most common cancer type among women worldwide, requires early detection and accurate diagnosis for improved treatment outcomes. Segmenting fat fibroglandular tissue (FGT) in magnetic resonance imaging (MRI) is essential creating volumetric models, enhancing surgical workflow, improving clinical Manual segmentation time-consuming subjective, prompting development of automated deep-learning algorithms to perform this task. However, configuring these 3D medical images...
Angiosarcoma is a very rare entity of soft tissue neoplasm with an aggressive and destructive biological behavior. Thyroid angiosarcoma usually reported in Alpine regions, only exceptionally cases arising non-mountainous areas. In the regions it constitutes 2-10% all malignant thyroid tumors.We report case non-Alpine 71-year-old female 10 years old multinodular goiter. The cervical mass underwent rapid growth last year, she was referred for surgical treatment. A 15cm found on right side neck...
Breast cancer image fusion consists of registering and visualizing different sets a patient synchronized torso radiological images into 3D model. spatial interpretation visualization by the treating physician can be augmented with patient-specific digital breast model that integrates images. But absence ground truth for good correlation between surface information has impaired development potential clinical applications.A new acquisition protocol was designed to acquire Magnetic Resonance...
The thyroid gland is a rare site of clinically detectable tumor metastasis. As tumors are usually assumed to be primary in origin, its recognition as secondary difficult.We report case an 80-year old female who was referred the Department Surgery for symptomatic nodule. Her medical history included radical nephrectomy renal cell carcinoma (RCC) nine years ago. During follow-up pancreatic nodule noted suggestive neuroendocrine and von Hippel-Lindau syndrome had ruled out. fine-needle...
When performing conservative surgery for breast cancer, reshaping can be a challenging procedure. Level 1 oncoplastic (OPS) techniques, i.e., advancement or rotation of glandular flaps, should performed when less than 20 per cent volume is excised.A new OPS technique described. A wide centro-lateral flap created after extensive undermining the skin and nipple-areolar complex, rotated into cavity.This use following excision, in glandular, not fatty, breasts, standard closure cavity would...
The clinical presentation of patients with soft-tissue sarcoma is highly variable. Most present a painless mass, typically one that increasing in size, and few have systemic symptoms such as fever, weight loss, or malaise. Soft tissue sarcomas can initially as, even be misdiagnosed deep venous thrombosis (DVT), leading to late diagnosis.A 51-year-old woman presented the hospital complaints pain swelling her left thigh, interpreted an infected hematoma associated vein treated accordingly....
Axillary staging in patients with complete response after neoadjuvant chemotherapy (NAC) is still controversial. Our objective was to test tattoo alone and subsequentially plus clip as markers the targeted axillary dissection of ycN0 patients.Prospective cohort cT1-T3, cN1 (proven histologically), M0 scheduled receive NAC. Exclusion criteria were lobular histology, prior surgery, clinical N2/3. In 1 this positive node (Neotarget node) tattooed at diagnosis. If ycN0, a performed. After an...