Lindsay N. Wright

ORCID: 0009-0006-9067-7825
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • Protein Structure and Dynamics
  • Probiotics and Fermented Foods
  • Neonatal and Maternal Infections

Concordia University
2024

Concordia University
2024

Antimicrobial peptides (AMPs) are of growing interest as potential candidates for antibiotics to which antimicrobial resistance increases slowly. In this article, we perform the first in silico study synthetic β sheet-forming AMP GL13K. Through atomistic simulations single and multipeptide systems under different charge conditions, able shine a light on short timescales early aggregation. We find that isolated peptide conformations primarily dictated by sequence rather than charge, whereas...

10.1101/2024.01.25.577308 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-01-28

Antimicrobial peptides (AMPs) are of growing interest as potential candidates that may offer more resilience against antimicrobial resistance than traditional antibiotic agents. In this article, we perform the first in silico study synthetic ß sheet-forming AMP GL13K. Through atomistic simulations single and multi-peptide systems under different conditions, able to shine a light on short timescales early aggregation. We find isolated peptide conformations primarily dictated by sequence...

10.1002/cbic.202400088 article EN cc-by-nc ChemBioChem 2024-04-04
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