A5101811054- Mitochondrial Function and Pathology
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- CRISPR and Genetic Engineering
- Heme Oxygenase-1 and Carbon Monoxide
- RNA and protein synthesis mechanisms
- Adipose Tissue and Metabolism
- Metabolism and Genetic Disorders
- Identification and Quantification in Food
- Neuroscience and Neuropharmacology Research
- Chromosomal and Genetic Variations
Universidad Autónoma de Madrid
2023
Instituto de Investigaciones Biomédicas Sols-Morreale
2021-2023
Harvard University
2020
Izmir University
2016-2017
Dokuz Eylül University
2016-2017
Neurotransmitters and peptide hormones are secreted into outside the cell by a vesicle fusion process. Although non-coding RNA (ncRNA) that include microRNA (miRNA) regulates gene expression inside where they transcribed, extracellular miRNA has been recently discovered cells, proposing might be released to participate in cell-to-cell communication. Despite its importance of miRNA, molecular mechanisms which can stored vesicles remain enigmatic. Using next-generation sequencing, purification...
Abstract We have exploited the repetitive nature of transposable elements human genome to generate synthetic circuits. Transposable such as LINE-1 and Alu successfully replicated in mammalian genomes throughout evolution reach a copy number ranging from thousands more than million. Targeting these with programmable DNA nucleases CRISPR-Cas9 rapidly induce extremely high levels cell death. use this genotoxic feature build biocontainment circuits: CRISPR defense system (CRISPR-DS) capable...
Abstract Neurotransmitters and peptide hormones are secreted into outside the cell by a vesicle fusion process. Although non-coding RNA (ncRNA) that include microRNA (miRNA) regulates gene expression inside where they transcribed, extracellular miRNA has been recently discovered cells, proposing might be released to participate in cell-to-cell communication. Despite its importance of miRNA, molecular mechanisms which can stored vesicles remain enigmatic. Using next-generation sequencing,...
Böbrek yetmezlikleri, organ fonksiyonlarında azalma ile kendini gösteren; her yaştaki hayvanda, özellikle yaşlı hayvanlarda çok görülen önemli bir hastalıktır. Özellikle kronik böbrek yetmezliği, geri dönüşümü olmayan karakterizedir ve en fazla tespit edilen hastalığıdır. hastalıklarında erken teşhis, etkili tedavi uygulamalarının yapılabilmesi açısından önem taşır. Kronik hastalığının tanısı, küçük hayvan pratiğinin parçasıdır. Kreatinin, hastalığın teşhisinde yetersiz kalmaktadır....