Sara Cristobal-Vargas

ORCID: 0009-0007-0109-6488
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About
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Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Invertebrate Immune Response Mechanisms
  • Telomeres, Telomerase, and Senescence

Universidad Autónoma de Madrid
2023

Programmed cell death (apoptosis) is a homeostasis program of animal tissues designed to remove cells that are unwanted or damaged by physiological insults. To assess the functional role apoptosis, we have studied consequences subjecting Drosophila epithelial defective in apoptosis stress genetic perturbations normally cause massive death. We find many those acquire persistent activity JNK pathway, which drives them into senescent status, characterized arrest division, hypertrophy, Senescent...

10.1038/s41420-023-01583-y article EN cc-by Cell Death Discovery 2023-08-02
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