A5005688962- Parathyroid Disorders and Treatments
- Cancer therapeutics and mechanisms
- Vitamin K Research Studies
- Bioactive Compounds and Antitumor Agents
- Muscle metabolism and nutrition
- Medicinal Plants and Bioactive Compounds
- Neurological and metabolic disorders
- Fungal Biology and Applications
- Multilingual Education and Policy
- Analytical Methods in Pharmaceuticals
- Nanoplatforms for cancer theranostics
- Linguistic Variation and Morphology
- Neutropenia and Cancer Infections
- Phytochemistry and Bioactivity Studies
- Porphyrin and Phthalocyanine Chemistry
- Cancer Treatment and Pharmacology
- Phytochemistry and Bioactive Compounds
- Photodynamic Therapy Research Studies
- Coenzyme Q10 studies and effects
- Renal function and acid-base balance
- Genetic and rare skin diseases.
- Cultural Heritage Materials Analysis
- Hume's philosophy and hair distribution
- Dementia and Cognitive Impairment Research
University of Insubria
2023-2024
Istituti di Ricovero e Cura a Carattere Scientifico
1979-1981
Antibacterial fluoroquinolones have emerged as potential anticancer drugs, thus prompting the synthesis of novel molecules with improved cytotoxic characteristics. Ciprofloxacin and norfloxacin derivatives, previously synthesized by our group, showed higher potency than their progenitors. However, no information about mechanisms action was reported. In this study, we selected most active among these promising evaluated, on a panel breast (including those triple-negative) bladder cancer cell...
Photodynamic therapy (PDT) is an anticancer/antibacterial strategy in which photosensitizers (PSs), light, and molecular oxygen generate reactive species induce cell death. PDT presents greater selectivity towards tumor cells than conventional chemotherapy; however, PSs have limitations that prompted the search for new molecules featuring more favorable chemical-physical characteristics. Curcumin its derivatives been used PDT. However, low water solubility, rapid metabolism, interference...