A5023448297- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Photoreceptor and optogenetics research
- Neuroscience and Neural Engineering
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Functional Brain Connectivity Studies
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Electrochemical Analysis and Applications
Georgia Institute of Technology
2016-2025
Emory University
2020-2025
The Wallace H. Coulter Department of Biomedical Engineering
2020-2025
The Ohio State University
2014
Rapid sensory adaptation is observed across all systems, and strongly shapes percepts in complex environments. Yet despite its ubiquity likely necessity for survival, the mechanistic basis poorly understood. A wide range of primarily vitro anesthetized studies have demonstrated emergence at level primary cortex, with only modest signatures earlier stages processing. The nature rapid how it representations during wakefulness, thus potential role perceptual adaptation, underexplored, as are...
Numerous studies have shown that neuronal representations in sensory pathways are far from static but instead strongly shaped by the complex properties of inputs they receive. Adaptation dynamically shapes neural signaling underlies our perception world yet remains poorly understood. We investigated rapid adaptation across timescales hundreds milliseconds to seconds through simultaneous multi-electrode recordings ventro-posteromedial nucleus thalamus (VPm) and layer 4 primary somatosensory...
As the tools to simultaneously record electrophysiological signals from large numbers of neurons within and across brain regions become increasingly available, this opens up for first time possibility establishing details causal relationships between monosynaptically connected patterns neural activation that underlie perception behavior. Although recorded activity synaptically has served as cornerstone much what we know about synaptic transmission plasticity, largely been relegated ex vivo...
Numerous studies have shown that neuronal representations in sensory pathways are far from static but instead strongly shaped by the complex properties of inputs they receive. Adaptation dynamically shapes neural signaling underlies our perception world yet remains poorly understood. We investigated rapid adaptation across timescales hundreds milliseconds to seconds through simultaneous multi-electrode recordings ventro-posteromedial nucleus thalamus (VPm) and layer 4 primary somatosensory...
Sensory signals from the outside world are transduced at periphery, passing through thalamus before reaching cortex, ultimately giving rise to sensory representations that enable us perceive world. The thalamocortical circuit is particularly sensitive temporal precision of thalamic spiking due highly convergent synaptic connectivity. Thalamic neurons can exhibit burst and tonic modes firing strongly influence timing within thalamus. impact these changes in state on encoding however, remains...
Abstract/Summary As the tools to simultaneously record electrophysiological signals from large numbers of neurons within and across brain regions become increasingly available, this opens up for first time possibility establishing details causal relationships between monosynaptically connected patterns neural activation that underlie perception behavior. Although recorded activity synaptically has served as cornerstone much what we know about synaptic transmission plasticity, largely been...
Abstract Rapid sensory adaptation is observed across all systems, and strongly shapes percepts in complex environments. Yet despite its ubiquity likely necessity for survival, the mechanistic basis poorly understood. A wide range of primarily in-vitro anesthetized studies have demonstrated emergence at level primary cortex, with only modest signatures earlier stages processing. The nature rapid how it representations during wakefulness, thus potential role perceptual adaptation,...
Abstract Sensory signals from the outside world are transduced at periphery, passing through thalamus before reaching cortex, ultimately giving rise to sensory representations that enable us perceive world. The thalamocortical circuit is particularly sensitive temporal precision of thalamic spiking due highly convergent synaptic connectivity. Thalamic neurons can exhibit burst and tonic modes firing strongly influence timing within thalamus. impact these changes in state on encoding however,...