A5070540986- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Apelin-related biomedical research
- Blood Pressure and Hypertension Studies
- Platelet Disorders and Treatments
- Hereditary Neurological Disorders
- Hair Growth and Disorders
- Dupuytren's Contracture and Treatments
- Optimism, Hope, and Well-being
- Dialysis and Renal Disease Management
- Blood groups and transfusion
Guangdong Provincial Hospital of Traditional Chinese Medicine
2021-2024
Guangzhou University of Chinese Medicine
2021-2023
Foshan Hospital of TCM
2021
Chronic kidney disease (CKD) is a leading public health issue associated with high morbidity worldwide. However, there are only few effective therapeutic strategies for CKD. Emodin, an anthraquinone compound from rhubarb, can inhibit fibrosis in tissues and cells. Our study aims to investigate the antifibrotic effect of emodin underlying molecular mechanism. A unilateral ureteral obstruction (UUO)-induced rat model was established evaluate on renal development. Hematoxylin eosin staining,...
The 2017 Oxford classification of immunoglobulin A nephropathy (IgAN) recently reported that crescents could predict a worse renal outcome. Early prediction crescent formation can help physicians determine the appropriate intervention, and thus, improve outcomes. Therefore, we aimed to establish nomogram model for in IgA patients.We retrospectively analyzed 200 cases biopsy-proven IgAN patients. Least absolute shrinkage selection operator(LASSO) regression multivariate logistic was applied...
This study aimed to develop two predictive nomograms for the assessment of long-term survival status in hemodialysis (HD) patients by examining prognostic factors all-cause mortality and cardiovascular (CVD) event mortality.A total 551 HD with an average age over 60 were included this study. The patients' medical records collected from our hospital randomly allocated cohorts: training cohort (n=385) validation (n=166). We employed multivariate Cox assessments fine-gray proportional hazards...
<b><i>Introduction:</i></b> A working group on the Oxford classification of IgA nephropathy (IgAN) recently reported that crescents detected in kidney tissue predicted a worse renal outcome. However, effect C1 lesion (crescents &#x3c;1/4th all glomeruli) and their volume prognosis IgAN is still unclear. We explored association with patients without obvious chronic lesions (glomerulosclerosis &#x3c;25%, T score &#x3c;2)....