A5113756525- Liver Disease Diagnosis and Treatment
- Species Distribution and Climate Change
- Pharmaceutical and Antibiotic Environmental Impacts
- Fatty Acid Research and Health
- Wildlife Ecology and Conservation
- Antibiotics Pharmacokinetics and Efficacy
- Chronic Kidney Disease and Diabetes
- Crafts, Textile, and Design
- Diabetes and associated disorders
- Fuel Cells and Related Materials
- Advanced battery technologies research
- Epigenetics and DNA Methylation
- Organic Chemistry Cycloaddition Reactions
- Alcohol Consumption and Health Effects
- High voltage insulation and dielectric phenomena
- Diet and metabolism studies
- Nuclear Structure and Function
- Power Transformer Diagnostics and Insulation
- Optimism, Hope, and Well-being
- Free Radicals and Antioxidants
- Glycosylation and Glycoproteins Research
- Animal Ecology and Behavior Studies
- Ferroptosis and cancer prognosis
- Insect and Pesticide Research
- Tumors and Oncological Cases
Capital Medical University
2023-2025
China Agricultural University
2025
International Bamboo and Rattan Organization
2024
Shanghai Jiao Tong University
2023-2024
Anhui University of Traditional Chinese Medicine
2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2024
Zhejiang University
2024
Vanderbilt University Medical Center
2024
Wuhan Polytechnic University
2024
Guangxi University
2023
In this study, the influence of total sn-2 palmitic triacylglycerols (TAGs) and ratio 1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO) in human milk fat substitute (HMFS) on metabolic changes were investigated Sprague–Dawley rats. Metabolomics lipidomics profiling analysis indicated that increasing TAGs OPL OPO HMFS could significantly glycine, serine threonine metabolism, glycerophospholipid glycerolipid sphingolipid bile acid biosynthesis, taurine...
Chronic kidney disease (CKD) is a leading public health issue associated with high morbidity worldwide. However, there are only few effective therapeutic strategies for CKD. Emodin, an anthraquinone compound from rhubarb, can inhibit fibrosis in tissues and cells. Our study aims to investigate the antifibrotic effect of emodin underlying molecular mechanism. A unilateral ureteral obstruction (UUO)-induced rat model was established evaluate on renal development. Hematoxylin eosin staining,...
Baculoviruses can induce climbing behavior in caterpillar hosts, which provides an excellent model for studying parasite manipulation of host behavior. Herein, we found that Helicoverpa armigera single nucleopolyhedrovirus (HearNPV) promoted lipid metabolism infected H. larvae, and changes affect Therefore, understanding the molecular mechanisms between is particularly important. In this study, adipokinetic hormone 1 (HaAKH1), 2 (HaAKH2) their receptor HaAKHR were essential promoting...
Random skin flap is commonly used for the repair of craniofacial defects. However, ischemic necrosis frequently detected postoperatively, which severely affects patients' prognosis and quality life, especially those with diabetes. Although nitrate has been found to protect against development diseases, its effects on injury in diabetic flaps remains be thoroughly explored. This study investigated survival associated mechanisms. The results showed that increased blood perfusion decreased area...
In this study, the impact of sn-2 palmitic triacyclglycerols (TAGs) in combination with their ratio two major TAGs (1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO)) human milk fat substitute (HMFS) on bile acid (BA) metabolism and intestinal microbiota composition was investigated newly-weaned Sprague–Dawley rats after four weeks high-fat feeding. Compared those control group rats, HMFS-fed had significantly increased contents six hepatic primary BAs...
In this study, the effect of sn-2 palmitic triacylglycerols (sn-2 TAGs) and ratio between two major TAGs (OPL to OPO ratio) in a human milk fat substitute (HMFS) on growth, fatty acid calcium absorptions, lipid bile metabolic alterations was investigated Sprague-Dawley rats. After 4 weeks high-fat feeding, rats fed with HMFS containing content 57.87% an OPL 1.4 showed lowest TAG accumulation their livers hypertrophy perirenal adipocytes, compared groups fats lower or ratio. Meanwhile,...
Transformer oil plays the role of heat dissipation and insulation in power transformers, its electrical thermal characteristics are directly related to stable operation transformer. At same time, it is important master electric–thermal transformer for state evaluation, latent fault prediction, maintenance planning. Based on this, gas production rule under accelerated aging studied this paper. First, experimental platform established accelerate transformers. Second, taken as research object,...
DCLRE1B is a 5'-to-3' exonuclease, which involved in repairing ICL-related DNA damage. has been reported to cause poor prognosis variety of cancers. Nonetheless, there no research on DCLRE1B's biological role pan-cancer datasets. Thus, ascertaining the processes via modulates tumorigenesis was goal extensive bioinformatics investigation datasets present research.In our research, employing internet websites and databases including TIMER, GEPIA, TISIDB, Kaplan-Meier Plotter, SangerBox,...
Glycosyltransferases (GTs) are pivotal enzymes involved in glycosidic bond synthesis, which can lead to either retention or inversion of the glycosyl moiety's anomeric configuration. However, catalytic mechanism for retaining GTs remains a subject controversy. In this study, we employ MD and QM/MM metadynamics investigate double-displacement β-Kdo transferase WbbB. Our findings demonstrate that nucleophile Asp232 initiates reaction by attacking sugar ring containing carboxylate at position,...
Oxidative derivatives of triacylglycerols (ox-TGs), aldehydes, and 3-monochloropropane-1,2-diol esters (3-MCPDE) were simultaneously evaluated in a 90-day subchronic study, focusing on biological indicators, biochemical serum metabolomics as the first part integrated toxicity interactions. After 90 days feeding Kunming mice, coexposure to combined toxicants significantly inhibited trend liver weight gain, reduced levels total bilirubin (TBIL) direct (DBIL), decreased uric acid (UA) compared...
In this study, three-dimensional quantitative conformational relationship (3D-QSAR) analysis was conducted on 38 known anthraquinone derivatives. Additionally, five pH-responsive photosensitizers (A1 to A5) were designed and synthesized through addition, elimination, substitution mechanisms using the derivative rhubarb phenol as raw material. The structures of products characterized 1H-NMR, 13C-NMR, LCMS, UV-Vis absorption spectra fluorescent at different pH values obtained. To investigate...