- Advanced Radiotherapy Techniques
- Nuclear physics research studies
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Head and Neck Cancer Studies
- Radiation Therapy and Dosimetry
- Astronomical and nuclear sciences
- Atomic and Subatomic Physics Research
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Oral health in cancer treatment
- Radiation Detection and Scintillator Technologies
- Ear Surgery and Otitis Media
- Lung Cancer Diagnosis and Treatment
- Nuclear Physics and Applications
- Radiation Dose and Imaging
- Respiratory and Cough-Related Research
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Nuclear Materials and Properties
- Molten salt chemistry and electrochemical processes
- Medical Image Segmentation Techniques
- Atomic and Molecular Physics
- Chemical Synthesis and Characterization
Royal Manchester Children's Hospital
2023-2025
University of Manchester
2024-2025
Manchester University NHS Foundation Trust
2023-2025
Manchester Academic Health Science Centre
2023-2024
ViewRay (United States)
2007-2016
Washington University in St. Louis
1995-2015
University of California, Los Angeles
2015
Université de Rouen Normandie
2015
Laboratoire d'Informatique, du Traitement de l'Information et des Systèmes
2015
University of Florida
2002-2007
The three-body decay $^{12}\mathrm{O}\ensuremath{\rightarrow}2p+^{10}\mathrm{C}$ was studied following production via single-neutron stripping from a radioactive $^{13}\mathrm{O}$ projectile. This is the first observation of two-proton emission an unbound ground state where one-proton channel energetically closed beyond lightest case $^{6}\mathrm{Be}$. No evidence for $^{2}\mathrm{He}$ seen, despite predictions large diproton branching ratio. An upper limit 7% (95% C.L.) established this...
gel (MGS Research, Inc., Guilford, CT) has been evaluated for measuring intensity-modulated radiation therapy (IMRT) dose distributions. Treatment plans with target doses of 1500 cGy were generated by the Peacock IMRT system (NOMOS Corp., Sewickley, PA) using test volumes. The gels enclosed in 13 cm outer diameter cylindrical glass vessels. Dose calibration was conducted seven smaller (4 diameter) vessels irradiated to 0–1800 300 increments. Three-dimensional maps proton relaxation rate...
The production of intermediate mass fragments (IMF's) from the four reactions 55A MeV $^{124,136}\mathrm{Xe}$ + $^{112,124}\mathrm{Sn}$ is studied with an experimental apparatus which highly efficient for detection both charged particles and neutrons. IMF's are more localized in midvelocity region than light particles, detected multiplicity depends linearly on charge lost projectile increases neutron excess system. Remnants projectile, very little velocity reduction, found most reaction...
We present an evaluation of the precision and accuracy image-based radiochromic film (RCF) dosimetry performed using a commercial RCF product (Gafchromic MD-55-2, Nuclear Associates, Inc.) high-spatial resolution (100 μm pixel size) He–Ne scanning-laser film-digitizer (Personal Densitometer, Molecular Dynamics, as optical density (OD) imaging system. The this system are evaluated by performing in well characterized conformal external beam brachytherapy high dose-rate (HDR) radiation fields....
High energy \ensuremath{\gamma} rays from the decay of giant resonance in hot ${}^{120}$Sn nuclei were measured excitation range 30--130 MeV. The excited populated by inelastic scattering \ensuremath{\alpha} particles at 40 and 50 MeV/nucleon. width was observed to increase monotonically with increasing energy, 5 MeV ground state $\ensuremath{\sim}12$ largest energy. Inelastic predominantly populates low angular momentum states, is thus attributed fluctuations nuclear shape induced temperature.
To evaluate xerostomia following intensity-modulated radiation therapy (IMRT).An institutional review board-approved study of was conducted in 210 head and neck cancer patients who were beyond the acute recovery phase (> 1 year) after therapy. Xerostomia evaluated with 8-question XQ developed validated at University Michigan.Median scores (normalized so that no = 0 maximum 100) larynx-only group, 4 points, ipsilateral radiotherapy, 34 points; bilateral 64 IMRT mean contralateral parotid dose...
Abstract Background The mucopolysaccharidoses are a group of rare, inherited metabolic disorders. MPS II is X-linked recessive disease, also known as Hunter syndrome. Clinical manifestations include upper and lower respiratory tract, head neck pathologies influencing quality life, morbidity, mortality. Medical surgical intervention outcomes for reported inconsistently, creating challenge when synthesising contrasting evidence. This study set out to address the inconsistency in outcome...
Multiplicities of intermediate-mass fragments (IMFs), neutrons, and charged particles were measured for ${}^{112}\mathrm{Sn}{+}^{112}\mathrm{Sn}$ ${}^{124}\mathrm{Sn}{+}^{124}\mathrm{Sn}$ at $E/A\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}40\mathrm{MeV}$. Significantly different scalings the mean IMF multiplicities with neutron charged-particle are observed two reactions. These differences can be qualitatively understood in terms fragment emission from an expanding evaporating source...
Summary Many wetlands around the world are vulnerable to invasive species and also culturally important for Indigenous peoples. Yet, translating complex values peoples hold into management actions mitigate impacts of can be difficult put practice. In this paper, we draw on an Indigenous‐led project Nardab wetland in Kakadu National Park show how understanding local nuance priorities different places guide more effective inclusive weed activities. At Nardab, guided choice three priority sites...
Intracavitary vaginal applicators typically incorporate internal shielding to reduce dose the bladder and rectum. While distributions about a single colpostat have been extensively measured calculated, these studies neglect dosimetric perturbations arising from contralateral or intrauterine tandem. Dosimetric effects of inhomogeneities in brachytherapy is essential for both dose-based implant optimization as well comparison with alternate modalities, such intensity modulated radiation...
The creation of a clustered and neutron-rich midvelocity (``neck'' or ``hot spot'') region in intermediate-energy heavy-ion collisions is discussed. Reaction simulations suggest that the preponderance species isotopic isobaric ratios results primarily from amplification initial neutron excess due to $d$ (and by inference $\ensuremath{\alpha}$-particle) cluster formation.
Despite recent advances in radiochromic film and gel dosimetry techniques, radiation therapy still lacks an efficient, accurate, convenient dose measurement method capable of measuring the simultaneously over a plane or volume (3D). A possibility for creating such 3D based on observing scintillation photons emitted from irradiated was recently reported [A. S. Kirov et al., Med. Phys. 26 , 1069 (1999)]. In present article, we investigate potential to use liquid solution (LS) as sensitive...
Plastic scintillator (PS) has been proposed for both one- and two-dimensional (1D 2D) dose measurements radiation therapy applications. For low-energy photon modalities (e.g., brachytherapy), an efficient water equivalent is needed. To perform 2D measurements, a high localization of the scintillation process required. Guided by comparison mass energy absorption coefficients as function distribution distance from radioactive source, modeled Monte Carlo transport simulation, small quantity...
Light fragments (d, t, 3He,4He) were measured for central collisions of 112Sn+112Sn and 124Sn+124Sn at E/A=40 MeV. While individual isotope ratios depend strongly on the neutron-to-proton ratio entrance channel, double RH–He=[Y(d)Y(4He)]/[Y(t)Y(3He)] shows no such sensitivity. Within assumptions Albergo thermometric technique, this independence is consistent with attainment full chemical equilibrium each reaction same common temperature. However, also predicted by calculations based emission...
Neutrons and charged light intermediate-mass products from the ${}^{197}\mathrm{Au}{+}^{86}\mathrm{Kr}$ reaction at ${E}_{\mathrm{lab}}/A=35 \mathrm{MeV}$ were measured with $4\ensuremath{\pi}$ angular coverage, in coincidence projectilelike (PLFs) targetlike fragments (TLFs). The characteristics of PLF TLF yields their correlation neutron, light-charged particles, (IMFs) are consistent a scenario where essentially all collisions proceed through dissipative stage. It is found that damping...
For each patient receiving definitive treatment for cervix cancer, several CT/MR imaging studies need to be registered in order specify the total physical or biological dose fixed tissue voxel an organ system. This turns out a difficult problem due large localized deformations and displacements of bladder, rectum, vagina, uterus paracervical tissues tumor regression, bladder rectal filling variations, especially insertion applicator itself. paper explores utility using fluid landmark image...
Purposes: The purposes of this study were to examine dose alterations gross tumor volume (GTV) and lung using heterogeneity corrections predict the magnitude these changes. Methods: Three separate conformal plans generated for 37 patients with cancer: plan 1 corrected heterogeneity, 2 did not correct 3 used identical beams monitor units from but heterogeneous calculations. Plans normalized 95% isodose line. Mean (MeanDGTV), maximum (MaxDGTV), minimum (MinDGTV) GTV V20 compared between 3. For...