A5093320388- Atherosclerosis and Cardiovascular Diseases
- IL-33, ST2, and ILC Pathways
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiovascular Disease and Adiposity
- Vitamin D Research Studies
Queen Mary University of London
2023-2024
Cancer Research UK
2023-2024
Atrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke heart failure. Here we investigated how immune infiltrate human epicardial adipose tissue (EAT), which directly overlies myocardium, contributes to AF. Flow cytometry analysis revealed enrichment tissue-resident memory T (T
Abstract A major challenge for inhibiting metastasis is the ability of cancer cells to reversibly switch states in response microenvironmental cues along metastatic cascade. The regulatory factors and signals from microenvironment enabling colorectal (CRC) transition into an invasive state establish liver remain unknown. Using a combination single-cell multiomics spatial transcriptomics data primary CRC patients, we reveal putative metastasis-initiating with regenerative inflammatory...
<title>Abstract</title> Atrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke heart failure. Here, we investigate how immune infiltrate human epicardial adipose tissue (EAT), which directly overlies myocardium, contributes to AF. Flow cytometry analysis revealed enrichment tissue-resident memory T (T<sub>RM</sub>) cells in AF patients. Cellular indexing transcriptomes epitopes by sequencing (CITE-Seq) single-cell TCR sequencing, identified...