A5031920474- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- ECG Monitoring and Analysis
- FOXO transcription factor regulation
- GDF15 and Related Biomarkers
- Enhanced Oil Recovery Techniques
- Esophageal Cancer Research and Treatment
- Photonic and Optical Devices
- Nephrotoxicity and Medicinal Plants
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Advanced Memory and Neural Computing
- Acute Myocardial Infarction Research
- Cardiac Fibrosis and Remodeling
- Gastrointestinal disorders and treatments
- Circular RNAs in diseases
- Hydrocarbon exploration and reservoir analysis
- Cancer, Lipids, and Metabolism
- Gastric Cancer Management and Outcomes
- Heart Failure Treatment and Management
Fujian Medical University
2023-2025
Fujian Provincial Cancer Hospital
2023-2024
Huazhong University of Science and Technology
2023
Yangtze University
2022
Soochow University
2019-2021
Sichuan University
2021
Sudden cardiac death (SCD), which can deprive a person of life within minutes, is destructive heart abnormality. Thus, providing early warning information for patients at risk SCD, especially those outside hospitals, essential. In this study, we investigated the performances ensemble empirical mode decomposition (EEMD)-based entropy features on SCD identification. EEMD-based were obtained by using following technology: (1) EEMD was performed HRV beats to decompose them into intrinsic...
Colorectal liver metastasis (CRLM) is challenging in the clinical treatment of colorectal cancer. Limited research has been conducted on how CRLM develops. RNA sequencing data were obtained from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA). Four machine learning algorithms used to screen hub CRLM-specific genes, including Least Absolute Shrinkage Selection Operator (Lasso), Random forest, SVM-RFE, XGboost. model for identifying was developed using stepwise logistic...
Hepatocellular carcinoma (HCC) treatment remains challenging, particularly for immune checkpoint inhibitors (ICIs) non-response patients. Spatial transcriptome (ST) data and machine learning algorithms offer new insights into understanding HCC heterogeneity ICIs resistance mechanisms. Utilizing ST from patients on treatment, we analyzed pathway activity infiltration. We combined 167 models to develop a G2M-checkpoint related signature (G2MRS) based differential gene expression. The four...
Coronary artery disease (CAD) is a life-threatening condition that, unless treated at an early stage, can lead to congestive heart failure, ischemic disease, and myocardial infarction. Early detection of diagnostic features underlying electrocardiography signals crucial for identifying treating CAD. In the present work, we proposed novel entropy called Renyi Distribution Entropy (RdisEn) analysis short-term rate variability (HRV) Our simulation experiment with synthetic, physiological,...
Myocardial infarction (MI) is a common cardiovascular disease and leading cause of death worldwide. The etiology MI complicated not completely understood. Many risk factors are reported important for the development MI, including lifestyle factors, environmental psychosocial genetic etc. Identifying individuals with an increased urgent major challenge improving prevention. knowledge base (MIRKB) developed facilitating research goal MIRKB to collect models related increase efficiency systems...
Heart failure (HF) is a cardiovascular disease with high incidence around the world. Accumulating studies have focused on identification of biomarkers for HF precision medicine. To understand heterogeneity and provide biomarker information personalized diagnosis treatment HF, knowledge database collecting distributed multiple-level necessary.In this study, (HFBD) was established by manually data from literature in PubMed. HFBD contains 2618 records 868 (731 single 137 combined) extracted...
The basic performance of a novel high-efficiency spontaneous imbibition agent (SXJ-2) was investigated in this study. mechanisms and wettability reversal an oil-wet sandstone surface (OSS) by SXJ-2 were studied infrared (IR) analysis, scanning electron microscopy (SEM), zeta potential determination, wetting angle experiment, determination work. interfacial tension between oil water for the system is relatively low. has better than other systems altering higher recovery under same time...
Abstract The phenotype–genotype relationship is a key for personalized and precision medicine complex diseases. To unravel the complexity of clinical network, we used cardiovascular diseases (CVDs) associated non-coding RNAs (ncRNAs) (i.e. miRNAs, long ncRNAs, etc.) as case study CVDs at systems or network level. We first integrated database ncRNAs (CVDncR, http://sysbio.org.cn/cvdncr/) to construct CVD–ncRNA networks annotate their associations. characterize networks, then separated miRNAs...
Cellular senescence is a cellular response to stress, including the activation of oncogenes, and characterized by irreversible proliferation arrest. Restricted studies have provided relationship between immunotherapy for esophageal cancer.In present study, we obtained clinical sample colon cancer from TCGA database senescence-related genes MSigDB Genecard datasets. prognostic were identified WGCNA, COX, lasso regression analysis, risk score (CSRS) was calculated. We constructed model based...
In acute aristolochic acid nephropathy (AAN), (AA) induces renal injury and tubulointerstitial fibrosis. However, the roles of microRNAs (miRNAs/miRs) mRNAs involved in AAN are not clearly understood. The aim present study was to examine AA‑induced genome‑wide differentially expressed (DE) miRNAs DE using deep sequencing mouse kidneys, analyze their regulatory networks. self‑controlled study, mice were treated with 5 mg/kg/day AA for days, following unilateral nephrectomy. fibrosis detected...
Background Gastric gastrointestinal stromal tumors in challenging anatomical locations are difficult to remove. Methods This study retrospectively analyzed the clinical data of 12 patients with gastric GISTs who underwent robot-assisted laparoscopic combined endoscopic partial gastrectomy (RALE-PG) and manual suturing wall. Results included a mean age 56.8 ± 9.8 years BMI 23.9 1.9 kg/m 2 . Tumors were located GEJ ( n = 3), lesser curvature posterior wall 3) antrum 3). The cardia pylorus...
An indirectly heated GeTe microwave switch is designed in this work. The multiphysics simulation software COMSOL used to optimize the structure, and associated performance of simulated analyzed. By embedding a high thermal conductivity isolation layer low oxide trench, energy loss during heat transfer significantly reduced, thereby power time required for switching states are decreased. Simulation results show that non-crystallization process reduced by 106ns crystallization 861ns, at...