About
Contact & Profiles
A5030069571
Research Areas
- Chemical Synthesis and Characterization
- Ammonia Synthesis and Nitrogen Reduction
- Ubiquitin and proteasome pathways
- Fungal and yeast genetics research
- 14-3-3 protein interactions
- DNA and Nucleic Acid Chemistry
New York University
2023
Tandem DNA repeats are often organized into heterochromatin that is crucial for genome organization and stability. Recent studies revealed individual within tandem can behave very differently. How assembled distinct structures remains poorly understood. Here, we developed a genome-wide genetic screen using reporter gene at different units in repeat array. This led to identification of conserved protein Rex1BD required silencing. Our structural analysis forms four-helix bundle structure with...
10.1073/pnas.2309359120
article
EN
cc-by-nc-nd
Proceedings of the National Academy of Sciences
2023-12-04
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