A5082178502- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Fibrosis and Remodeling
- Angiogenesis and VEGF in Cancer
- Congenital heart defects research
- T-cell and B-cell Immunology
- Nitric Oxide and Endothelin Effects
- Glycosylation and Glycoproteins Research
- Receptor Mechanisms and Signaling
- Cellular Mechanics and Interactions
- Electrical Fault Detection and Protection
- Cyclopropane Reaction Mechanisms
- Pluripotent Stem Cells Research
- Axon Guidance and Neuronal Signaling
- Fluorine in Organic Chemistry
- Electromagnetic Compatibility and Noise Suppression
- Sirtuins and Resveratrol in Medicine
- Crystallization and Solubility Studies
- Power Systems Fault Detection
- Monoclonal and Polyclonal Antibodies Research
- Adipose Tissue and Metabolism
- Synthesis and Biological Evaluation
- Electrostatic Discharge in Electronics
- Silicon Carbide Semiconductor Technologies
Hubei University of Medicine
2011-2019
Henan University
2018
Shangqiu Normal University
2017
Taihe Hospital
2009-2010
Nanyang Medical College
2009
The objective of this study was to investigate whether vascular endothelial growth factor (VEGF) secreted by mesenchymal stem cells (MSC) improves myocardial survival and the engraftment implanted MSC in infarcted hearts promotes recruitment through paracrine release stromal cell-derived factor-1α (SDF-1α). VEGF-expressing (VEGFMSC)-conditioned medium enhanced SDF-1α expression heart slices H9C2 cardiomyoblast via VEGF receptor (VEGFR). VEGFMSC-conditioned markedly promoted cardiac cell...
In addition to its multipotent capability, the mesenchymal stem cell (MSC) can secrete and supply a large amount of vascular endothelial growth factor (VEGF). The stromal-derived factor-1 alpha (SDF-1alpha) plays an important role in homing cells injured tissues heart. Therefore, MSCs over-expressing SDF-1alpha could augment angiogenesis pathway.In vitro, differentiation into endothelial-like was induced by cultivation 10% foetal calf serum 50 ngml(-1) or specific inhibitors for nitrous...
Acetylcholine (ACh) plays an important role in neural and non-neural function, but its mesenchymal stem cell (MSC) migration remains to be determined. In the present study, we have found that ACh induces MSC via muscarinic acetylcholine receptors (mAChRs). Among several mAChRs, MSCs express mAChR subtype 1 (m1AChR). interaction with mAChR1. MEK1/2 inhibitor PD98059 blocks ERK1/2 phosphorylation while partially inhibiting ACh-induced migration. InsP3Rs 2-APB inhibits MAPK/ERK completely...
The objective of this study is to determine if exuberant sympathetic nerve activity involved in muscle satellite cell differentiation and myoblast fusion. By using immunoassaying western blot analyses, we found that β1 β2-adrenergic receptors (AdR) were expressed C2C12 cells. differentiated cells exhibited an increased expression β2-AdR, as compared with the proliferating Continuous exposure isoprenaline (ISO), a β-AdR agonist, delayed differentiation, fusion time- dose-dependent manner. ISO...
Stromal cell-derived factor 1α (SDF-1) is not only a major chemotactic factor, but also an inducer of angiogenesis. The effects SDF-1α on the left ventricular remodeling in rat myocardial infarction (MI) model were analyzed. Myocardial was induced by ligation coronary artery rats. 0.5 × 1010 pfu/ml AdV-SDF-1 or Adv-LacZ immediately injected into infarcted myocardium, 120 μl cell-free PBS region wall control, and sham group, respectively. We found that group had higher LVSP ±dP/dtmax, lower...
Abstract Distribution network grounding fault testing technology relies on a single criterion, which has positioning blind area, resulting in large ranging error. In this paper, test for distribution based zero sequence power direction determination is proposed. The from the supply side to load terminal specified as positive of network, equivalent current modeled, and high-frequency component transient containing main characteristics extracted. line determined direction. For line, less than...