A5027890721- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Public Health and Nutrition
- Cancer-related gene regulation
- Birth, Development, and Health
- Folate and B Vitamins Research
- Ubiquitin and proteasome pathways
- Radiation Therapy and Dosimetry
- RNA modifications and cancer
- Diet, Metabolism, and Disease
- Effects of Radiation Exposure
- Cardiovascular Disease and Adiposity
- Nutritional Studies and Diet
Mianyang Central Hospital
2022-2024
University of Electronic Science and Technology of China
2022-2024
Jinan University
2019-2023
Lactate, a metabolic byproduct, has gained recognition as highly influential signaling molecule. Lactylation, an emerging form of post-translational modification derived from lactate, plays crucial role in numerous cellular processes such inflammation, embryonic development, tumor proliferation, and metabolism. However, the precise molecular mechanisms through which lactylation governs these biological functions both physiological pathological contexts remain elusive. Hence, it is imperative...
Objective Clinical relevance of global DNA methylation and one‐carbon metabolite levels with histological severity remains uncertain in patients nonalcoholic fatty liver disease (NAFLD). This study aimed to evaluate hepatic serum concentrations NAFLD the possible associations these parameters histology. Methods Liver biopsies from 18 control participants 47 were evaluated. Results The level was significantly lower group than among overweight. Participants moderate inflammation mild fibrosis...
β-Carotene has been reported to alleviate hepatic steatosis (SS), inflammation, and fibrosis in vivo vitro studies. However, the clinical relevance of serum β-carotene β-carotene-to-retinol (SC/SR) ratio with histological severity nonalcoholic fatty liver disease (NAFLD) patients is unknown. This case-control study enrolled 24 control subjects 62 NAFLD patients. Liver biopsies were collected characteristics assessed. Information regard demographic, anthropometric dietary intake was assessed...
Previous research has shown maternal betaine supplementation alleviates fetal-derived hepatic steatosis. Therefore, this study examined the anti-inflammatory effect of intake in offspring mice and its mechanism.Female C57BL/6J their were randomly divided into 3 groups according to treatment received during gestation lactation: control diet (CD), fatty liver disease (FLD), + 1% (FLD-BET). The FLD group was given a high-fat streptozotocin (HFD STZ), FLD-BET treated with HFD STZ betaine. After...
Background A healthy diet in a college student life is critical to ensure their normal growth, study and development. Aim In order accurately assess the dietary pattern of students guide it, our aims evaluate validity instant photography as an alternative assessment method students. Methods Nine participants were enrolled given presentation on methods, including weighing, 24-hour recall, photography. The took pictures foods from three angles before after eating for constant seven days,...