Beatrice Schleupner

ORCID: 0009-0007-4132-0317
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About
Contact & Profiles
Research Areas
  • Microplastics and Plastic Pollution
  • Effects and risks of endocrine disrupting chemicals
  • Electron and X-Ray Spectroscopy Techniques
  • Recycling and Waste Management Techniques
  • biodegradable polymer synthesis and properties
  • Advanced Electron Microscopy Techniques and Applications
  • Phytochemical compounds biological activities
  • Force Microscopy Techniques and Applications
  • Bioeconomy and Sustainability Development
  • Bioactive Compounds and Antitumor Agents
  • Microbial bioremediation and biosurfactants
  • Chemokine receptors and signaling
  • Sarcoma Diagnosis and Treatment
  • Beetle Biology and Toxicology Studies
  • Bone Tumor Diagnosis and Treatments
  • Silk-based biomaterials and applications
  • Cancer Research and Treatments
  • Ubiquitin and proteasome pathways
  • Integrated Circuits and Semiconductor Failure Analysis

Duke University Hospital
2024-2025

Duke Medical Center
2023-2024

Duke University
2024

Virginia Tech
2018-2019

Carilion Clinic
2018

Microplastics are routinely ingested and inhaled by humans other organisms. Despite the frequency of plastic exposure, little is known about its health consequences. Of particular concern additives─chemical compounds that intentionally or unintentionally added to plastics improve functionality as residual components production. Additives often loosely bound polymer may be released during exposures. To better understand effects additives, we performed a comprehensive literature search compile...

10.1021/acs.est.3c06840 article EN cc-by Environmental Science & Technology 2024-06-03

Liquid-cell electron microscopy is a rapidly growing field in the imaging domain. While real-time observations are readily available to analyze materials and biological systems, these measurementshave been limited two-dimensional (2-D) image plane. Here, we introduce an exciting technical advance 3-D while enclosed liquid. The development of liquid-cell tomography permitted us observe quantify host–pathogen interactions solution contained vacuum system microscope. In doing so, demonstrate...

10.1021/acs.nanolett.9b01309 article EN Nano Letters 2019-06-19

Purpose. Recently, the association between ATRX and a more aggressive sarcoma phenotype has been shown. We performed retrospective study of sarcomas from an individual institution to evaluate as prognosticator in soft tissue sarcoma. Experimental Design. 128 were collected single stained for ATRX. The prognostic significance these markers was evaluated smaller cohort primary (n = 68). Kaplan–Meier curves created univariate analysis, Cox regression utilized multivariate analysis. Results....

10.1155/2024/4001796 article EN cc-by Sarcoma 2024-05-06

Abstract Plastics are the most prevalent human-made substance in world and ubiquitous throughout all ecosystems. Microscopic plastic particles routinely ingested inhaled by humans other organisms. Despite frequency of exposures, little is known about their health consequences. Of particular concern additives -chemical compounds that mixed into plastics to improve functionality or unintentionally acquired during production use. Additives loosely bound polymer may be released exposures. These...

10.1101/2023.06.30.547246 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-07-02

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10.1017/s1431927618001836 article EN Microscopy and Microanalysis 2018-08-01

Abstract BACKGROUND: Psoralen is a natural ultraviolet activated compound that has been used for over 70 years to treat skin cancer, psoriasis, and vitiligo. Recently, expand its use beyond external treatment, novel therapeutic called X-PACT (X-ray psoralen cancer therapy) was created internal tumors. A combination of 8-methoxypsoralen phosphors convert low doses x-ray radiation (UV) light are injected into solid tumors subsequently by photons with considerable antineoplastic effect....

10.1158/1538-7445.am2024-6642 article EN Cancer Research 2024-03-22

Abstract Plastic waste has accumulated rapidly in the past century and is now found throughout every ecosystem on Earth. Its ubiquitous presence means that plastic routinely ingested by countless organisms, with potential negative consequences for organismal health. New solutions are urgently needed to combat pollution. Among many strategies required curb pollution crisis, bioremediation of via enzymatic activity microbial species represents a promising approach. Diverse microbes harbor...

10.1101/2024.04.12.589142 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-04-12
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