Sihan Jia

ORCID: 0009-0007-4158-8663
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Research Areas
  • Acute Myocardial Infarction Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Acupuncture Treatment Research Studies
  • Nanoplatforms for cancer theranostics
  • Advanced Nanomaterials in Catalysis
  • Cardiovascular Disease and Adiposity
  • Coronary Interventions and Diagnostics
  • Organoboron and organosilicon chemistry
  • Inflammasome and immune disorders
  • Nanoparticle-Based Drug Delivery
  • Traditional Chinese Medicine Studies
  • Cardiac Imaging and Diagnostics
  • Atherosclerosis and Cardiovascular Diseases
  • Heart Failure Treatment and Management
  • Radical Photochemical Reactions
  • Pulmonary Hypertension Research and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Medical Research and Treatments
  • Advancements in Battery Materials
  • Mitochondrial Function and Pathology
  • Carbon dioxide utilization in catalysis
  • Fuel Cells and Related Materials
  • Catalytic C–H Functionalization Methods
  • Advanced Battery Materials and Technologies
  • Asymmetric Synthesis and Catalysis

Beijing Hospital of Traditional Chinese Medicine
2021-2025

Capital Medical University
2021-2025

Henan Normal University
2022-2025

Xiamen University
2022-2023

Beijing University of Chinese Medicine
2019

Beijing City University
2016

The integration of reactive oxygen species (ROS)-based chemodynamic therapy (CDT) and photodynamic (PDT) has attracted enormous attention for synergistic antitumor therapies. However, the strategy is severely hampered by tumor hypoxia overproduced antioxidant glutathione (GSH) in microenvironment. Inspired concept metal coordination-based nanomedicines, we proposed an effective cancer treatment response to special microenvironmental properties. Herein, present novel metal-coordinated...

10.1021/acsbiomaterials.2c00076 article EN ACS Biomaterials Science & Engineering 2022-03-31

Herein, we report a method for the regioselective alkylation and phosphonation of quinoline C4–H via B3H7-mediated nucleophilic addition Turbo Grignard reagents phosphine oxide anions to quinolines bearing different substituents, affording 4-alkyl 4-phosphoryl tetrahydroquinolines after one-pot oxidation or reduction. The results indicate that coordination B3H7 group can activate substrates toward potential 1,4-dearomative subtly control regioselectivity by preventing 1,2-dearomative addition.

10.1021/acs.orglett.4c04713 article EN Organic Letters 2025-01-01

Comprehensive Summary N ‐Methylimidazole borane adducts were synthesized and their reactivities with different electrophiles after deprotonation compared. Subsequently, we used the more stable reactive imidazole B 3 H 7 , a multinuclear borane, to generate various C2, C2 benzyl, C2,5‐disubstituted of under mild reaction conditions. Some 2,5‐disubstituted products are usually difficult synthesize directly from molecules. Furthermore, moiety these can be easily removed obtain corresponding...

10.1002/cjoc.202401190 article EN Chinese Journal of Chemistry 2025-01-27

Peri-procedural myocardial injury (PMI) is a common complication of percutaneous coronary intervention (PCI), which cannot be entirely avoided using available treatments. The findings earlier research have shown that Shen-Yuan-Dan (SYD) capsules, traditional Chinese medicine, can potentially alleviating PMI. This study aimed to confirm further this hypothesis in rigorous, well-designed randomized controlled study.Our clinical trial was randomized, double-blinded, and placebo-controlled. A...

10.1016/j.ctim.2022.102841 article EN cc-by Complementary Therapies in Medicine 2022-05-25

To observe the therapeutic effect of body acupuncture combined with auricular in treatment woman menopause insomnia induced by disharmony between heart and kidney.A total 111 outpatients menopausal were randomly divided into group (n=55, acupoints plus points) control (n=56, acupoints). For group, Shenmen (HT7), Sanyinjiao (SP6), Anmian, Zhaohai (KI6), Shenmai (BL62), Sishencong (EX-HN1), Xinshu (BL15) Shenshu (BL21) needled filiform needles, HT7, SP6, BL15 BL21 also stimulated...

10.13702/j.1000-0607.180390 article EN PubMed 2019-07-25

All-solid-state K batteries are ideal energy storage devices for grid-scale applications of renewable energies. A novel electrolyte K[B3H7NH2BH2NH2B3H7] with weakly coordinating anions was synthesized. It has a high K+ conductivity 1.01 × 10-4 S cm-1 at 75 °C, which is probably due to the increased electrostatic potential and size anions.

10.1039/d2cc00408a article EN Chemical Communications 2022-01-01

Peri-procedural myocardial injury (PMI) during percutaneous coronary intervention (PCI) will result in an unfavorable clinical prognosis patients, thus urgently necessitating effective drug treatment measures. Shen-Yuan-Dan (SYD) capsules are a traditional Chinese medicine (TCM) preparation that have been found to potential protection effects the peri-procedural phase of PCI previous and basic research; however, there is lack rigorous, randomized, controlled studies. The aim this study...

10.21037/atm.2018.09.44 article EN Annals of Translational Medicine 2019-03-01

This study aimed to conduct a visual analysis of the relevant literature on mitochondrial dynamics in heart failure, explore research progress, frontier topics, and development trends this field, provide references for concerning prevention treatment failure. The Web Science was searched from inception October 1, 2023 identify English Bibliometric methods were utilized statistically analyze eligible literature, CiteSpace 6.2.R5 software employed visualize data such as countries publication,...

10.1097/md.0000000000037598 article EN cc-by-nc Medicine 2024-03-15

To compare the pain thresholds of acupoints in meridians related to irritable bowel syndrome(IBS) between IBS patients and healthy people.Thirty-four adults were collected into a normal group,and 60 with arranged an group. Pain detected on large intestinal,small intestinal,stomach,spleen,gallbladder some commone use for by measuring apparatus three times. Bilateral jing-well,xing-spring,shu-stream,jing-river,he-sea,front mu-alarm,lower he-sea,yuan-primary,luo-connecting back shu-transport...

10.13703/j.0255-2930.2016.08.015 article EN PubMed 2016-08-12
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