A5092944213- Treatment of Major Depression
- Mental Health Research Topics
- Stress Responses and Cortisol
- Functional Brain Connectivity Studies
- Memory and Neural Mechanisms
- Anesthesia and Sedative Agents
- Neurotransmitter Receptor Influence on Behavior
- Anesthesia and Neurotoxicity Research
- Hypothalamic control of reproductive hormones
- Nicotinic Acetylcholine Receptors Study
- Ovarian function and disorders
Medical University of Vienna
2023-2024
Hong Kong Polytechnic University
2023
Among its pleiotropic properties, gender-affirming hormone therapy (GHT) affects regional brain volumes. The hypothalamus, which regulates neuroendocrine function and associated emotional cognitive processes, is an intuitive target for probing GHT effects. We sought to assess changes hypothalamus hypothalamic subunit volumes after GHT, thereby honouring the region's anatomical functional heterogeneity.Individuals with gender dysphoria cisgender controls underwent 2 MRI measurements, a median...
Ketamine exerts rapid antidepressant effects by enhancing neuroplasticity, particularly in the amygdala and hippocampus-regions involved fear processing learning. While role of ketamine's dissociative its response is debated, anxiety experienced during infusion has been negatively correlated with treatment outcomes. In this single-blind, placebo-controlled study, a subset 17 healthy volunteers (6 males, 23.12 ± 1.9 years) received intravenously placebo first 0.5 mg/kg racemic ketamine second...