A5101444912- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Atomic and Subatomic Physics Research
- Alzheimer's disease research and treatments
- Histiocytic Disorders and Treatments
- Robotic Mechanisms and Dynamics
- Electronic and Structural Properties of Oxides
- Neuroscience and Neuropharmacology Research
- Metastasis and carcinoma case studies
- Blockchain Technology Applications and Security
- Lanthanide and Transition Metal Complexes
- Nuclear Physics and Applications
- Semiconductor materials and devices
- Luminescence and Fluorescent Materials
- Parvovirus B19 Infection Studies
- Advanced X-ray and CT Imaging
- Distributed systems and fault tolerance
- Iterative Learning Control Systems
- Geophysics and Gravity Measurements
- Breast Implant and Reconstruction
- Cloud Computing and Resource Management
- Advanced Radiotherapy Techniques
- Piezoelectric Actuators and Control
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
Beijing Tongren Hospital
2022-2025
Capital Medical University
2022-2025
Huazhong University of Science and Technology
2010-2024
Beijing Children’s Hospital
2022
Wuhan National Laboratory for Optoelectronics
2020
Harvard University
2018
Massachusetts General Hospital
2018
Inner Mongolia Medical University
2013
Fluorescent dextrans are commonly used as macropinocytic probes to study the properties of endocytic cargoes; however, effect size on mechanisms has not been carefully analyzed. By using chemical and siRNA inhibition individual pathways, we evaluated internalization two dextrans, Dex10 (dextran 10 kDa) Dex70 70 kDa), in mammalian HeLa cells Caenorhabditis elegans coelomocytes. We revealed that enters these cell types predominantly via clathrin- dynamin-independent amiloride-sensitive...
A significant hallmark of Alzheimer's disease is the formation senile plaques in brain due to unbalanced levels amyloid-beta (Aβ). However, although how Aβ produced from amyloid precursor proteins well understood, little known regarding clearance and metabolism various aggregates brain. Similarly, astrocytes internalize degrade Aβ, are play an important role plaque maintenance clearance. The objective this study investigate cellular mechanisms that mediate internalization soluble monomeric...
To minimize parallax errors and achieve high spatial resolution positron emission tomography (PET) systems, developing depth-of-interaction (DOI) encoding detectors has become a significant research topic. In this paper, we investigated dual-ended readout PET detector based on the multi-voltage threshold sampling method combined with convolutional neural network to calculate pulse's energy (MVT-CNN method). The MVT was used acquire time-threshold samples digitize scintillation pulses. CNN...
Multivoltage threshold (MVT) is an all digital scintillation pulse sampling method with advantages over traditional analog-digital mixed approaches in positron emission tomography (PET). However, MVT has limitations energy calculation the whole spectrum. We constructed a convolutional neural network (CNN) to establish accurate mapping between samples and values. acquired signals from five single-channel detectors oscilloscope. The CNN was trained one detector tested on detectors. It compared...
The depth-of-interaction (DOI) information can reduce parallax errors and improve the spatial resolution of positron emission tomography (PET) imaging. Current DOI detectors, with either single-ended readout design or dual-ended design, usually require substantial changes to crystal arrays and/or electronics. In this work, we proposed a estimation approach minimal in detector hardware using supervised machine learning algorithm, random forest (RF). energy value measured from one end crystal,...
Rosai-Dorfman disease (RDD) is an uncommon, benign, and idiopathic histiocytic proliferative disorder. Multiple intracranial RDD extremely rare treatment varies.
Increasingly popular decentralized applications (dApps) with complex application logic incur significant overhead for executing smart contract transactions, which greatly limits public blockchain performance. Pre-executing transactions off the critical path can mitigate substantial I/O and computation costs during execution. However, pre-execution does not yield any state transitions, rendering system inconsistent actual This inconsistency lead to deviations in paths when processing...
Objective To study the clinical manifestations,diagnosis and surgical treatment of tubular adenoma in extrahepatic bile duct.Methods The data 3 patients with duct who were admitted to Affiliated Hospital Inner Mongolia Medical University from July 2010 February 2012 retrospectively analyzed.Results tumors located at middle lower part common duct.All received resection Roux-en-Y cholangioenterostomy,and recovered well.The results pathological examination showed that all adenoma,and 2 had...
During PET scanning, motion of animals can result in severe artifacts the image. In this paper, we proposed a novel correction method for freely moving using histo-images and deblurring neural network. The was tested on resolution phantom cylindrical phantom, both which obtained good results. initial results show promise performing network to generate high-quality images.
How to calculate the gravitational waves (GWs) of Extreme-mass-ratio-inspirals (EMRIs) in a highly accurate and efficient way still keeps challenge. In this paper, we present so-called fully recalibrated waveforms for EMRIs with high accuracy. Based on numerical data by solving Teukolsky equations, recalibrate all mass-ratio independent coefficients factorized which are used effective-one-body (EOB) models. Due these new coefficients, precision is improved enormously, much higher than...
Three amyloid beta (Ab) PET tracers have been approved by FDA for clinical applications. However, they are only exclusion of Alzheimer's disease (AD), but not positive imaging diagnosis AD. This strongly suggests that more sensitive probes AD urgently needed. The fundamental limitation the three is primarily capable detecting insoluble Aβs, toxic soluble Aβs. In course SAR (structure-activity-relationship) investigation curcumin analogues CRANAD-X (X = 2, 3, 5, 58, etc) we found...
Objective: To explore the surgical strategy of nipple areola complex (NAC) management in central breast cancer. Methods: A retrospective analysis was conducted on 164 cases cancer who underwent surgery treatment from December 2017 to 2020 Breast Center Beijing Tongren Hospital, Capital Medical University. Prior surgery, tumor-nipple distance (TND) and maximum diameter tumor were measured by magnetic resonance imaging (MRI). The presence invagination, discharge, ulceration (including Paget's...