A5031892105- Bacterial biofilms and quorum sensing
- Child Nutrition and Water Access
- Bacterial Genetics and Biotechnology
- Cell Image Analysis Techniques
- Viral gastroenteritis research and epidemiology
- Fecal contamination and water quality
- Streptococcal Infections and Treatments
- Vibrio bacteria research studies
- Blood groups and transfusion
- Food Security and Health in Diverse Populations
- Otolaryngology and Infectious Diseases
- Image Processing Techniques and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Herpesvirus Infections and Treatments
- Oral and Maxillofacial Pathology
- Bacillus and Francisella bacterial research
- Child Nutrition and Feeding Issues
- Lymphatic System and Diseases
University of Iowa Hospitals and Clinics
2024
Carilion Clinic
2024
Virginia Tech
2024
Georgia Institute of Technology
2019-2023
We conducted a controlled before-and-after trial to evaluate the impact of an onsite urban sanitation intervention on prevalence enteric infection, soil transmitted helminth re-infection, and diarrhea among children in Maputo, Mozambique. A non-governmental organization replaced existing poor-quality latrines with pour-flush toilets septic tanks serving household clusters. enrolled aged 1–48 months at baseline measured outcomes before 12 24 after intervention, concurrent measurement...
Bacteria can be highly social, controlling collective behaviors via cell-cell communication mechanisms known as quorum sensing (QS). QS is now a large research field, yet basic question remains unanswered: what the environmental resolution of QS? The notion threshold, or “quorum,” separating coordinated ON and OFF states central dogma in QS, but recent studies have shown heterogeneous responses at single cell scale.
This case uniquely provides radiographic and histopathologic correlates offering insight into the poorly understood disorder of symptomatic sialosis (sialadeneosis). Sialosis is often managed conservatively, with surgical intervention reserved for cases refractory to conservative management. The rarely employed treatment highlighted in this patient by relief presenting symptoms accompanied later complications.
When grown on agar surfaces, microbes can produce distinct multicellular spatial structures called colonies, which contain characteristic sizes, shapes, edges, textures, and degrees of opacity color. For over one hundred years, researchers have used these morphology cues to classify bacteria guide more targeted treatment pathogens. Advances in genome sequencing technology revolutionized our ability bacterial isolates while genomic methods are the ascendancy, morphological characterization...
Abstract We conducted a controlled before-and-after trial to evaluate the impact of an onsite urban sanitation intervention on prevalence enteric infection, soil transmitted helminth re-infection, and diarrhea among children in Maputo, Mozambique. A non-governmental organization replaced existing poor-quality latrines with pour-flush toilets septic tanks serving household clusters. enrolled aged 1-48 months at baseline measured outcomes before 12 24 after intervention, concurrent measurement...
Present follow-up data comparing transoral and transfacial parotid gland procedures for stone removal to offer insight addressing technical considerations complications.
The relationship between enteric pathogen exposure and long-term health effects like stunting cognitive deficiencies may be mediated, in part, by environmental dysfunction (EED). We aimed to assess whether access a shared sanitation intervention affected the concentration of biomarkers intestinal inflammation permeability stool young children living Maputo, Mozambique. Maputo Sanitation trial was controlled before-and-after study onsite low-income, unplanned urban neighborhoods collected...
Lymphedema is a chronic condition characterized by dysfunction of the lymphatic system. There currently no available cure. The standard care complete decongestive physiotherapy performed lymphedema therapist. However, may flare between appointments, making home important. are several medical devices to treat at home, but they can be expensive, noisy, and bulky, restricting patient mobility. Thus, there demand for other that utilized appointments. overall goal this research study assess...
Abstract Objective(s) Present a clinically challenging case of an immunocompetent 74‐year‐old male who presented with marked dyspnea and hemoptysis. After the airway was secured, direct laryngoscopy revealed large, fungating, hemorrhagic mass left lateral pharyngeal wall surrounding structures. Methods Chart review single patient. This patient provided consent for his materials images to be used educational purposes publication. Results The clinical appearance suspicious aggressive neoplasm....
Abstract Quorum sensing (QS) is a mechanism of cell–cell communication that connects gene expression to environmental conditions (e.g. density) in many bacterial species, mediated by diffusible signal molecules. Current functional studies focus on dichotomy QS on/off (or, quorate / sub-quorate) states, overlooking the potential for intermediate, graded responses shifts environment. Here, we track regulated protease ( lasB ) and show Pseudomonas aeruginosa can deliver behavioral response...
Abstract When grown on agar surfaces, microbes can produce distinct multicellular spatial structures called colonies, which contain characteristic sizes, shapes, edges, textures, and degrees of opacity color. For over one hundred years, researchers have used these morphology cues to classify bacteria guide more targeted treatment pathogens. Advances in genome sequencing technology revolutionized our ability bacterial isolates while genomic methods are the ascendancy, morphological...