- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- Surgical Simulation and Training
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Anatomy and Medical Technology
- Radiation Therapy and Dosimetry
- Robotic Path Planning Algorithms
- Robotics and Sensor-Based Localization
- Radioactivity and Radon Measurements
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Augmented Reality Applications
- Simulation-Based Education in Healthcare
- Medical Imaging and Pathology Studies
- Radiation Detection and Scintillator Technologies
- Digital Radiography and Breast Imaging
- Modular Robots and Swarm Intelligence
- Cardiovascular Function and Risk Factors
- Bone health and osteoporosis research
- Radiomics and Machine Learning in Medical Imaging
- Radiation Effects and Dosimetry
- Advances in Oncology and Radiotherapy
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac, Anesthesia and Surgical Outcomes
King's College London
2008-2024
Spital Linth
2024
Athens Medical Center
1989-2022
National and Kapodistrian University of Athens
2010-2020
Hartford Hospital
2020
University of Central Florida
2020
Florida College
2020
Penn Center for AIDS Research
2020
University of Pennsylvania Health System
2020
Houston Methodist
2020
Objective: To demonstrate the noninferiority of fundamentals robotic surgery (FRS) skills curriculum over current training paradigms and identify an ideal platform. Summary Background Data: There is currently no validated, uniformly accepted for in skills. Methods: Single-blinded parallel-group randomized trial at 12 international American College Surgeons (ACS) Accredited Education Institutes (AEI). Thirty-three experts 123 inexperienced surgical trainees were enrolled between April 2015...
BackgroundIndividuals with serum antibodies to citrullinated protein antigens (ACPA), rheumatoid factor, and symptoms, such as inflammatory joint pain, are at high risk of developing arthritis. In the arthritis prevention in pre-clinical phase abatacept (APIPPRA) trial, we aimed evaluate feasibility, efficacy, acceptability treating individuals T-cell co-stimulation modulator abatacept.MethodsThe APIPPRA study was a randomised, double-blind, multicentre, parallel, placebo-controlled, 2b...
There are well-established predisposing factors for the development of metabolic syndrome (MetS) in childhood or adolescence, but no specific risk profile has been identified as yet. The Prediction Metabolic Syndrome Adolescence (PREMA) study was conducted (1) to construct a classification score that could detect children at high MetS adolescence and (2) test its predictive accuracy.In derivation cohort (1270 children), data from natal parental initial laboratory assessment 6 8 years age...
In view of their superior soft tissue contrast compared to computed tomography, magnetic resonance images are commonly involved in stereotactic radiosurgery/radiotherapy applications for target delineation purposes. It is known, however, that geometrically distorted, thus deteriorating dose delivery accuracy. The present work focuses on the assessment geometric distortion inherent used treatment planning and attempts quantitively evaluate consequent impact delivery. distortions 3 clinical...
3% of kidney transplant recipients return to dialysis annually upon allograft failure. Development antibodies (Ab) against human leukocyte antigens (HLA) is a validated prognostic biomarker We tested whether screening for HLA Ab, combined with an intervention improve adherence and optimization immunosuppression could prevent failure.Prospective, open-labelled randomised biomarker-based strategy (hybrid) trial in 13 UK centres [EudraCT (2012-004308-36) ISRCTN (46157828)]. Patients were...
Purpose: The aim of this work is the dosimetric validation a deterministic radiation transport based treatment planning system ( BRACHYVISION ™ v. 8.8, referred to as TPS in following) for multiple source dwell position brachytherapy applications employing shielded applicator homogeneous water geometries. Methods: calculations an irradiation plan seven VS2000 high dose rate (HDR) positions and partially (GM11004380) were compared corresponding Monte Carlo (MC) simulation results, well...
Purpose: To measure the output factors (OFs) of small fields formed by variable aperture collimator system (iris) a CyberKnife (CK) robotic radiosurgery system, and determine correction for microchamber four diode detectors. Methods: OF measurements were performed using PTW PinPoint 31014 microchamber, detectors (PTW‐60017, −60012, −60008, SunNuclear EDGE detector), TLD‐100 microcubes, alanine dosimeters, EBT films, polymer gels 5 mm, 7.5 10 12.5 15 mm iris collimators at 650 800 1000 source...
Purpose: The aim of this work is to implement a recently proposed dosimetric formalism for nonstandard fields the calibration and small field output factor measurement robotic stereotactic radiosurgery system. Methods: Reference dosimetry measurements were performed in nonstandard, 60 mm diameter machine specific reference (msr) using Farmer ion chamber, five other cylindrical chambers with cavity lengths ranging from 16.25 down 2.7 mm, alanine dosimeters. Output 5, 7.5, 10, 15 sizes...
Purpose: To compare TG43‐based and Acuros deterministic radiation transport‐based calculations of the BrachyVision treatment planning system (TPS) with corresponding Monte Carlo (MC) simulation results in heterogeneous patient geometries, order to validate quantify accuracy improvement it marks relative TG43. Methods: Dosimetric comparisons form isodose lines, percentage dose difference maps, volume histogram were performed for two voxelized mathematical models resembling an esophageal a...
Objective To evaluate the clinical impact of fluorodeoxyglucose (FDG)-PET/computed tomography (CT) scan on restaging breast cancer patients with rising tumor markers and negative or equivocal findings in conventional imaging studies. Methods We studied 46 an average age 57.6 years (ranging from 38 to 68 years). All were referred for FDG-PET/CT because elevated markers, without any other obvious laboratory sign relapse. Conventional study results either (29 out patients) inconclusive (17...
This work provides characterization of system-related geometric distortions present in MRIs used Gamma Knife (GK) stereotactic radiosurgery (SRS) treatment planning. A custom-made phantom, compatible with the Leksell frame model G and encompassing 947 control points (CPs), was utilized. MR images were obtained without frame, thus allowing discrimination frame-induced distortions. In absence following compensation for field inhomogeneities, measured average CP disposition owing to gradient...
Seeking to assess the radiation risk associated with radiological examinations in neonatal intensive care units, thermo-luminescence dosimetry was used for measurement of entrance surface dose (ESD) 44 AP chest and 28 combined chest-abdominal exposures a sample 60 neonates. The mean values ESD were found be equal +/- 16 microGy 43 19 microGy, respectively. MCNP-4C2 code mathematical phantom simulating neonate appropriate x-ray energy spectra employed simulation exposures. Equivalent organ...
Entrance surface radiation doses were measured with thermoluminescent dosimeters for 98 children who referred to a cardiology department the diagnosis or treatment of congenital heart disease. Additionally, all radiographic parameters recorded and Monte Carlo simulations performed estimation entrance dose effective conversion factors, in order further calculate each child.
Background Event-based annotation of surgical operations has not received much attention, mainly due to diversity the visual content. As a first attempt at retrieval events, we address problem detecting smoke produced by electrosurgery tasks. Methods After video decomposition into shots, grid particles is placed over initial frame. The advected with space–time optical flow and number ad hoc kinematic features are extracted. feature selection, one-class support vector machine employed for...
Introduction: This article focuses on the effectiveness of virtual reality (VR) simulation training for intravenous (IV) cannulation. We analyzed learning process in skills acquisition from groups with limited experience comparison performance experts. Methods: Novices (n = 20) and intermediates 23) trained nine IV cannulation scenarios a high-fidelity VR simulator (Virtual IV). Another three were performed before after (pre- postassessment). Pre-/postassessment was also undertaken by group...