A5019803043- Insect and Pesticide Research
- Parasitic Infections and Diagnostics
- Plant Virus Research Studies
- Vector-borne infectious diseases
- Insect Resistance and Genetics
- Toxin Mechanisms and Immunotoxins
- Insect-Plant Interactions and Control
- Heat shock proteins research
- Venomous Animal Envenomation and Studies
- Legume Nitrogen Fixing Symbiosis
- Bee Products Chemical Analysis
- Mosquito-borne diseases and control
- Insect Pest Control Strategies
- Polyamine Metabolism and Applications
- Aerosol Filtration and Electrostatic Precipitation
- High voltage insulation and dielectric phenomena
- Viral Infectious Diseases and Gene Expression in Insects
- Cyclone Separators and Fluid Dynamics
- Neurobiology and Insect Physiology Research
Jiangsu University of Science and Technology
2022-2025
China University of Petroleum, Beijing
2017
Nosema bombycis is a representative species of Microsporidia, and the pathogen that causes pebrine disease in silkworms. In process infection, polar tube N. injected into host cells. During proliferation, recruits mitochondria The general transcriptional corepressor Ssn6 contains six tetratricopeptide repeats (TPR) undertakes various important functions. this study, we isolated characterized Nbssn6 microsporidium bombycis. gene complete ORF 1182 bp length encodes 393 amino acid polypeptide....
CCT is a chaperonin which widely present in eukaryotic cells and mainly involves the folding assembly of cytoskeletal proteins β-tubulin actin. The alpha subunit CCT(CCTα) plays pivotal role protein(s) as an individuals or complexes. In this study, we report cloning, characterization expression CCTα Nosema bombycis (NbCCTα) for first time. NbCCTα gene contains complete ORF 1629 bp length that encodes 542-amino acid polypeptide. 59.662 kDa molecular weight size with isoelectric point (pI)...
Microsporidia, as unicellular eukaryotes, also have an endomembrane system for transporting proteins, which is essentially similar to those of other eukaryotes. In coat protein complex II (COPII) consists Sar1, Sec23, Sec24, Sec13, and Sec31 mediates transport from the endoplasmic reticulum (ER) Golgi apparatus. Sar1 central player in regulation vesicle formation reticulum. this study, we successfully cloned NbSar1, NbSec23-1, NbSec23-2, NbSec24-1, NbSec24-2, NbSec13, NbSec31-1, NbSec31-2...
Chaperonin containing tailless complex polypeptide 1 (CCT) is a molecular chaperone protein that consists of eight completely different subunits and assists in the folding newly synthesized peptides. The zeta subunit CCT regulatory factor for assembly cytoskeletal proteins as individuals or complexes. In this study, Nosema bombycis (NbCCTζ) identified first time. complete ORF NbCCTζ gene 1533 bp length encodes 510 amino acid polypeptide. IFA results indicate colocalized with actin β-tubulin...
Microsporidia are obligate intracellular parasites that can infect a wide range of vertebrates and invertebrates including humans insects, such as silkworm bees. The microsporidium
The main function of Sec61 complex is participating in the transport polypeptide chains across endoplasmic reticulum. In this study, we identified NbSec61α and NbSec61γ genes microsporidian Nosema bombycis for first time. Immunfluorescence localization showed that were mainly distributed perinuclear region N. different developmental phases. results qRT-PCR expression level was high early phase decreased middle late phases . After knockdown , all down-regulated. These suggest may play an...