A5061687289- Bone Metabolism and Diseases
- Connective tissue disorders research
- Bone health and osteoporosis research
- Renal Diseases and Glomerulopathies
St Vincents Institute of Medical Research
2024
The University of Melbourne
2024
St Vincent's Hospital
2024
Tan Tock Seng Hospital
2020
Preclinical models (typically ovariectomized rats and genetically altered mice) have underpinned much of what we know about skeletal biology. They been pivotal for developing therapies osteoporosis monogenic conditions, including osteogenesis imperfecta, achondroplasia, hypophosphatasia, craniodysplasias. Further therapeutic advances, particularly to improve cortical strength, require improved understanding more rigorous use reporting. We describe here how trabecular bone structure develop,...
Acute glomerulonephritis due to anti-GBM antibody disease is rare, estimated occur in fewer than one case per million population. Patients usually present with acute renal failure urinalysis showing proteinuria not nephrotic range and a nephritic sediment characterized by dysmorphic red cells.