- Forensic Anthropology and Bioarchaeology Studies
- Bone health and osteoporosis research
- Paleopathology and ancient diseases
- Pleistocene-Era Hominins and Archaeology
- Evolution and Paleontology Studies
- Morphological variations and asymmetry
- Bone Metabolism and Diseases
- Archaeology and ancient environmental studies
- Bone and Dental Protein Studies
- Pacific and Southeast Asian Studies
- Hip disorders and treatments
- Nutrition, Genetics, and Disease
- Bone Tumor Diagnosis and Treatments
- Indigenous Studies and Ecology
- Wildlife Ecology and Conservation
- Urological Disorders and Treatments
- Bone fractures and treatments
- Forensic and Genetic Research
- Orthopedic Surgery and Rehabilitation
- Paleontology and Evolutionary Biology
- dental development and anomalies
- Orthopaedic implants and arthroplasty
- Genetics, Bioinformatics, and Biomedical Research
- Forensic Entomology and Diptera Studies
- Primate Behavior and Ecology
Australian National University
2016-2024
The University of Queensland
2021-2024
Naturalis Biodiversity Center
2023-2024
University of Kent
2012-2022
National University College
2021
New Generation University College
2021
Universitas Halmahera
2019
Imperial College London
2016-2018
Preclinical models (typically ovariectomized rats and genetically altered mice) have underpinned much of what we know about skeletal biology. They been pivotal for developing therapies osteoporosis monogenic conditions, including osteogenesis imperfecta, achondroplasia, hypophosphatasia, craniodysplasias. Further therapeutic advances, particularly to improve cortical strength, require improved understanding more rigorous use reporting. We describe here how trabecular bone structure develop,...
Abstract Linear enamel hypoplasia (LEH) is a macroscopically detectable band‐like dental defect, which represents localized decrease in thickness caused by some form of disruption to child's health. Such deformations are utilized osteoarchaeological research as permanent markers childhood physiological stress and have been extensively studied numerous ancient human populations. However, currently there no such data for medieval populations from Canterbury, UK. Here, LEH examined the context...
Understanding the links between bone microstructure and human lifestyle is critical for clinical anthropological research into skeletal growth adaptation. The present study first to report correspondence socio-economic status variation in ancient humans. Products of femoral cortical remodeling were assessed using histological methods a large medieval sample (N = 450) which represented two distinct groups. Osteonal parameters recorded posterior midshaft sections from adult males 233) females...
Abstract Thalassemias are inherited blood disorders that found in high prevalences the Mediterranean, Southeast Asia and Pacific. These diseases provide varying levels of resistance to malaria proposed have emerged as an adaptive response these regions. The transition agriculture Holocene has been suggested influenced selection for thalassemia Mediterranean land clearance farming encouraged interaction between Anopheles mosquitos, vectors malaria, human groups. Here we document macroscopic...
Payable gold was discovered in New Zealand’s South Island 1861, bringing tens of thousands people to the Otago Province. Most were men with limited means and no local family. Archival records show that goldfields life associated significant risk disabling injury from earth falls, equine interactions, violence. Care usually provided shantytowns or rudimentary village hospitals. Until recently, archival have been primary gaining insight into injuries on goldfields. In 2018–2019, University...
The use of diagenetic alterations in bone microstructure (‘histotaphonomy’) as indicators funerary treatment the past and for post-mortem interval calculations forensic cases has received increasing attention last decade. Studies have used histological changes to conclude in-situ decomposition, mummification, infanticide interval. There been very little attempt experimentally validate links between depositional conditions, time-since-death microscopic human so that meaningful interpretations...
Histomorphometric analysis of human cortical bone has documented the occurrence secondary osteon variants. These include drifting osteons which form tails as they move erratically through cortex and Type II show partial resorption redeposition within cement line osteon. Little is known about biological significance these Prior studies suggested correlations with age, biomechanics, diet, mineral homeostasis. No study yet tested for variant associations static measures remodeling. In this...
Abstract Across mammalian species, the periodicity with which enamel layers form (Retzius periodicity) in permanent teeth corresponds average body mass and pace of life history. According to Havers–Halberg Oscillation hypothesis ( HHO ), Retzius RP ) is a manifestation biorhythm that also expressed lamellar bone. Potentially, these links provide basis for investigating aspects species’ biology from fossilized teeth. Here, we tested intra‐specific predictions this on skeletal samples human...
Abstract Evidence of a periodic biorhythm is retained in tooth enamel the form Retzius lines. The periodicity lines ( RP ) correlates with body mass and scheduling life history events when compared between some mammalian species. correlation has led to development inter‐specific Havers–Halberg oscillation HHO hypothesis, which holds great potential for studying aspects fossil species biology from teeth. Yet, our understanding if, or how, relates human skeletal growth limited. goal here...
Abstract Skeletal growth rates reconstructed from bone histology in extinct insular hippopotamids, elephants, bovids and sauropods have been used to infer dwarfism as a response island conditions. Limited published records of osteocyte lacunae densities (Ot.Dn), proxy for living proliferation, suggested slower rate metabolism giant mammals. Here, we test whether insularity might affected series small murine rodents Timor. Ten adult femora were selected fossil assemblage dated the Late...
The common wombat (Vombatus ursinus) is equipped with a set of physiological and morphological adaptations suited to fossorial lifestyle. These allow wombats engage in efficient scratch-digging maintaining low basal metabolic rate while living underground. While bone microstructure has been described for several subterranean animals, histology received very little attention date. Here, we present preliminary insights into modern adult V. ursinus (Mt Fairy, New South Wales) Pleistocene fossil...
Ethnohistoric accounts indicate that the people of Australia's Channel Country engaged in activities rarely recorded elsewhere on continent, including food storage, aquaculture and possible cultivation, yet there has been little archaeological fieldwork to verify these accounts. Here, authors report a collaborative research project initiated by Mithaka addressing this lack investigation. The results show substantial diverse record, numerous large stone quarries, multiple ritual structures...
The Havers-Halberg Oscillation (HHO) hypothesis links evidence for the timing of a biorhythm retained in permanent tooth enamel (Retzius periodicity) to adult body mass and life history traits across mammals. Potentially, these provide way access fossil species from teeth. Recently we assessed intra-specific predictions HHO on human children. We reported Retzius periodicity (RP) corresponded with thickness, cusp formation time, when calculated isolated deciduous proposed might not remain...
Modern humans have a slow and extended period of childhood growth, but to what extent this ontogenetic pathway was present in Neanderthals is debated. Dental development, linked the duration somatic growth across modern primates, main source for information about development variety fossil including humans. Studies Neanderthal permanent teeth report pace either similar recent or relatively accelerated. milk teeth, which form emerge before provide an opportunity determine pattern at birth....
Abstract Dwarfed insular mammals are of significant interest to evolutionary biology because their morphological and physiological adaptations triggered by variables inherent geographical isolation. One life history trait that is expected be modified in relation body size reduction extended longevity facilitated ecological parameters such as predator competitor release fluctuating resource availability. However, systematic examination extreme cases dwarfism difficult largely represented...