A5017214947- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Cancer Genomics and Diagnostics
- Glioma Diagnosis and Treatment
- Single-cell and spatial transcriptomics
- Immune cells in cancer
- Insect Resistance and Genetics
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Plant Water Relations and Carbon Dynamics
- CAR-T cell therapy research
- Cancer Cells and Metastasis
- Photosynthetic Processes and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Molecular Biology Techniques and Applications
- Plant Genetic and Mutation Studies
- Renal and related cancers
Tumor Hospital of Xinjiang Medical University
2024
Xinjiang Medical University
2024
Chinese Academy of Agricultural Sciences
2020-2024
Institute of Vegetables and Flowers
2020-2024
Abstract Background Aberrant intracellular or intercellular signaling pathways are important mechanisms that contribute to the development and progression of cancer. However, communication associated with ccRCC is currently unknown. The purpose this study was examine aberrant tumor cell-to-cell signals during ccRCC. Methods We conducted an analysis on scRNA-seq data 6 normal kidney tissues. This included sub clustering, CNV analysis, single-cell trajectory cell–cell transcription factor...
Abstract Triple‐negative breast cancer (TNBC) is often considered one of the most aggressive subtypes cancer, characterized by a high recurrence rate and low overall survival (OS). It notorious for posing challenges related to drug resistance. While there has been progress in TNBC research, mechanisms underlying chemotherapy resistance remain largely elusive. We collect single‐cell RNA sequencing (scRNA‐seq) data from five patients susceptible resistant cases. Comprehensive analyses...
Drought stress is a major abiotic factor affecting tomato production and fruit quality. However, the genes metabolites associated with responses to water deficiency rehydration are poorly characterized. To identify functional key metabolic pathways underlying drought recovery, drought-susceptible drought-tolerant inbred lines underwent transcriptomic metabolomic analyses. A total of 332 drought-responsive 491 rehydration-responsive core were robustly differentially expressed in both...
<title>Abstract</title> Background Diffuse gliomas, characterized by significant heterogeneity, are aggressive brain tumors that commonly harbor oncogenic mutations. Examining the evolutionary changes of circulating tumor DNA (ctDNA) in cerebrospinal fluid (CSF) provides a valuable approach for monitoring disease progression and informing treatment strategies. Methods To assess genetic alterations profiling associated with glioma, we conducted targeted sequencing ctDNA from CSF along matched...
Drought stress is a major abiotic factor affecting tomato production and fruit quality. However, the genes metabolites associated with responses to water deficiency rehydration are poorly characterized. To identify functional key metabolic pathways underlying drought recovery, drought-susceptible drought-tolerant inbred lines underwent transcriptomic metabolomic analyses. A total of 332 drought-responsive 491 rehydration-responsive core were robustly differentially expressed in both...
Abstract Background Eggplant ( Solanum melongena L.) is a thermophilic vegetable, and its yield quality are often affected by cold stress. Therefore, identifying the key genes mechanisms of tolerance has become significant topic in eggplant. qRT-PCR been widely used to analyse gene expression patterns, reliable reference necessary for this technique. Methods To select evaluate suitable qRT-PCR, 18 candidate selected from transcriptome sequence data were subjected analysis their stability...