- Traditional Chinese Medicine Analysis
- Medicinal Plant Pharmacodynamics Research
- Pharmacological Effects of Natural Compounds
- Flavonoids in Medical Research
- Food Quality and Safety Studies
- Antioxidants, Aging, Portulaca oleracea
- Biochemical effects in animals
- Glioma Diagnosis and Treatment
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Synthesis and biological activity
- Radiomics and Machine Learning in Medical Imaging
- Plant-based Medicinal Research
- Organ Transplantation Techniques and Outcomes
- Traditional Chinese Medicine Studies
- Brain Tumor Detection and Classification
Wuhan University of Science and Technology
2023-2024
The First Affiliated Hospital, Sun Yat-sen University
2012
Zhongshan Hospital
2012
Shanghai Institute of Organic Chemistry
2012
Fudan University
2012
Sun Yat-sen University
2012
In this study, the diagnostic performance of histogram features APT, DTI and DSC in predicting IDH mutation MGMT promoter methylation status gliomas was compared. Secondly, parameters from signal-time intensity curve significantly improved predictive model. Most importantly, combined logistic regression model with can evaluate tumor nature glioma more comprehensively obtain better performance, which is expected to become an imaging molecular marker for prediction genotyping future.
Four derivatives of niclosamide were designed and synthesized. Their inhibitory effects on proliferation migration human breast cancer cell line MDA-MB-231 studied. The activity four compounds the cells is better than that niclosamide, among which compound 5a nicotinate has strongest effect migration, with an IC50 value 11.489μm. It expected to become a candidate for further preclinical in vivo research. This article uses method comprehensively describe application computer images...
Introduction: Caspase-3 is associated with apoptosis and inflammation up-regulated by ischemia reperfusion injury, which plays a key role in renal allograft survival. The efficacy of caspase-3 siRNA administered into the porcine kidney hemoperfusate during cold preservation has been proved an isolated organ perfusion system, but not auto-transplant model. Methods: Left kidneys were retrieved from mini pigs minimal flushed Ringer's solution followed University Wisconsin (UW) solution. UW or...