A5020998911- Nutrition and Health in Aging
- Statistical Methods and Bayesian Inference
- Multiple Myeloma Research and Treatments
- Physical Activity and Health
- Statistical Methods and Inference
- Protein Degradation and Inhibitors
- Child Nutrition and Feeding Issues
- Health Systems, Economic Evaluations, Quality of Life
- Dysphagia Assessment and Management
- Plant chemical constituents analysis
- Diagnosis and Treatment of Venous Diseases
- Wound Healing and Treatments
- Balance, Gait, and Falls Prevention
- Pressure Ulcer Prevention and Management
- melanin and skin pigmentation
- Older Adults Driving Studies
- Diet and metabolism studies
- Insurance, Mortality, Demography, Risk Management
- Obesity and Health Practices
- Frailty in Older Adults
- Complement system in diseases
- Cerebral Palsy and Movement Disorders
- Advanced Statistical Methods and Models
- Data-Driven Disease Surveillance
- Advanced Statistical Process Monitoring
Friedrich-Alexander-Universität Erlangen-Nürnberg
2020-2025
University of Göttingen
2023
Universität Innsbruck
2023
A poor appetite affects up to 27% of community-dwelling older adults in Europe and is an early predictor malnutrition. Little known about the factors associated with appetite. The present study, therefore, aims characterise appetite.As part European JPI project APPETITE, data from 850 participants, aged ≥ 70 years Longitudinal Ageing Study Amsterdam (LASA) 2015/16 were analysed. Appetite during last week was assessed a five-point scale dichotomised into "normal" "poor". Binary logistic...
Abstract Background and aims Walking is the core physical activity of older persons. The assessment walking capacity increasingly important for clinical purposes research. Differences between tools protocols short walks to obtain gait characteristics can be responsible changes, e.g., in speed from 0.1 0.2 m/s. purpose this study was generate further knowledge harmonization and/or standardization walk-test assessing under supervised conditions. Methods For cross-sectional study, 150...
Poor appetite is considered a key factor in the development of malnutrition, link that can be explained by alterations dietary intake. Given limited data on characteristics community-dwelling older adults with poor appetite, present study aimed to examine whether associated lower nutrient intake and more unfavourable food choices.
Cycling has positive effects on health and the proportion of older cyclists is rising. However, risk for adults to be injured or killed by a bicycle accident increases. The aim ongoing project "Safer in Older Age (SiFAr)" promote safer cycling community-dwelling with structured, multi-component exercise training. SiFAr randomized, controlled trial duration 3 months intervention 6-9 follow-up. We address persons aged 65 years living area Nürnberg-Fürth-Erlangen (Germany) who are either 1)...
Abstract Background The risk of older adults being injured or killed in a bicycle accident increases significantly due to the age-related decline physical function. Therefore, targeted interventions for improve safe cycling competence (CC) are urgently needed. Methods “Safer Cycling Older Age” (SiFAr) randomized controlled trial investigated if progressive multi-component training program related improves CC adults. Between June 2020 and May 2022, 127 community-dwelling persons living area...
The development of physical functioning after a caesura in an aged population is still widely unexplored. Analysis this topic would need to model the longitudinal trajectories and simultaneously take terminal events (deaths) into account. Separate analysis both results biased estimates, since it neglects inherent connection between two outcomes. Thus, type data generating process best modelled jointly. To facilitate several software applications were made available. They differ formulation,...
At hospital discharge, many older patients are at health and nutritional risk, indicating a requirement for ongoing care. We aim to evaluate the effects of comprehensive individualized care by geriatric-experienced professionals, so-called “pathfinders”, on status (NS) after discharge. A total 244 (median age 81.0 years) without major cognitive impairment were randomized Intervention Group (IG: 123) or Control (CG: 121) 12-month intervention, with up 7 home visits 11 phone calls. The...
Bayesian structured additive quantile regression is an established tool for regressing outcomes with unknown distributions on a set of explanatory variables and/or when interest lies effects the more extreme values outcome. Even though variable selection exists, its scope limited. We propose use Normal Beta Prime Spike and Slab (NBPSS) prior in to aid researcher not only but also effect selection. compare NBPSS approach statistical boosting regression, current standard automated simulation...
Abstract Joint models for longitudinal and time-to-event data simultaneously model information to avoid bias by combining usually a linear mixed with proportional hazards model. This class has seen many developments in recent years, yet joint including spatial predictor are still rare the traditional formulation of part is accompanied computational challenges. We propose piecewise exponential hazard using counting process representation structured additive predictors able estimate...
Nutritional care and nutritional status may differ in older persons receiving informal (IC) or professional (PC) home further depend on the living situation, but little is known this regard. In analysis of a cross-sectional multicenter study, type care, were enquired 353 adults (≥65) IC PC, either with partner (LP), others (LO) alone (LA), was determined by BMI MNA®. For receivers, food shopping (IC-LP 94%, IC-LO 96%, IC-LA 92%) warm meals 89%, 90%, 71%) mainly provided relatives, whereas...
Zusammenfassung Hintergrund Geriatrische Patienten sind alters- und krankheitsbedingt für das Auftreten einer Wunde, die den funktionellen Status Lebensqualität beeinträchtigt, prädisponiert. Dieser Aspekt wurde bisher in dieser Population wenig untersucht. Ziel Das Studie war es, Einfluss von chronischer (cW) akuter Wunde (aW) auf objektiven funktionalen sowie wundbezogene subjektive bei hospitalisierten geriatrischen zu untersuchen. Methode In explorativen Querschnittsanalyse wurden Daten...
Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint are still rare the traditional proportional hazards formulation of part model is accompanied by computational challenges. We propose a with piece-wise exponential hazard using counting process representation structured additive predictors able to estimate (non-)linear, random effects. Its capabilities assessed simulation study comparing our approach an established one...
Extramedullary plasmacytoma (EMP) belongs to the category of non-Hodgkin's lymphoma and has very little or no systemic bone marrow involvement. Usually EMPs arise in soft tissue head neck region but can also be located other regions. Referring our publication 1999 (Cancer 85: 2305-14), we conducted a literature review from 2019, documenting analysing all published PUBMED, parallel, included own patients.
Das extramedulläre Plasmozytom (EMP) gehört zur den Non-Hodgkin-Lymphomen und tritt üblicherweise im Weichteilgewebe der Kopf- Halsregion aber auch in anderen Regionen auf. Aufbauend auf unserer Publikation von 1999 (Cancer 85:2305-14) haben wir eine Literaturrecherche bis 2019 durchgeführt alle PUBMED veröffentlichten EMPs dokumentiert analysiert parallel dazu eigene Patienten die Studie mit aufgenommen.