A5068909459- Genomics and Phylogenetic Studies
- Genetic Neurodegenerative Diseases
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- Dental Research and COVID-19
- Optical Imaging and Spectroscopy Techniques
Covenant University
2023
Abstract Tandem repeats (TRs) represent one of the largest sources genetic variation in humans and are implicated a range phenotypes. Here we present deep characterization TR based on high coverage whole genome sequencing from 3550 diverse individuals 1000 Genomes Project H3Africa cohorts. We develop method, EnsembleTR, to integrate genotypes four separate methods resulting high-quality at more than 1.7 million loci. Our catalog reveals novel sequence features influencing heterozygosity,...
Abstract Tandem repeats (TRs) represent one of the largest sources genetic variation in humans and are implicated a range phenotypes. Here we present deep characterization TR based on high coverage whole genome sequencing from 3,550 diverse individuals 1000 Genomes Project H3Africa cohorts. We develop method, EnsembleTR, to integrate genotypes four separate methods resulting high-quality at more than 1.7 million loci. Our catalog reveals novel sequence features influencing heterozygosity,...