A5045804410- Cancer Immunotherapy and Biomarkers
- Bladder and Urothelial Cancer Treatments
- Cancer Genomics and Diagnostics
- Genomics and Rare Diseases
- Lung Cancer Research Studies
- Meningioma and schwannoma management
- Ferroptosis and cancer prognosis
- Ion channel regulation and function
- Pulmonary Hypertension Research and Treatments
- Neuroendocrine Tumor Research Advances
- Imbalanced Data Classification Techniques
- Financial Distress and Bankruptcy Prediction
- Breast Cancer Treatment Studies
- Molecular Biology Techniques and Applications
- Neuroblastoma Research and Treatments
- Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
Wuhan University of Technology
2024
Institut Curie
2020-2021
Université Paris Sciences et Lettres
2020
Istituto Nazionale Biostrutture e Biosistemi
2020
Université de Lorraine
2017
Abstract Background Metaplastic breast cancer (MBC) is a rare form of characterized by an aggressive clinical presentation, with poor response to standard chemotherapy. MBCs are typically triple-negative cancers (TNBCs), frequently alterations genes the PI3K-AKT-mTOR and RTK-MAPK signaling pathways. The objective this study was determine PI3K MAPK pathway inhibitors in patient-derived xenografts (PDXs) targetable alterations. Methods We compared survival between other histological subtypes,...
High-throughput molecular profiling of solid tumours using core needle biopsies (CNB) allows the identification actionable alterations, with around 70% success rate. Although several studies have demonstrated utility small biopsy specimens for testing, there remains debate as to sensitivity less invasive fine-needle aspiration (FNA) compared CNB detect alterations. We aimed prospectively evaluate potential FNA such alterations in various tumour types cancer patients included SHIVA02 trial....