A5035785078- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Pancreatic function and diabetes
- Pituitary Gland Disorders and Treatments
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Treatment and Management
- Adrenal and Paraganglionic Tumors
- Lung Cancer Research Studies
- Thyroid and Parathyroid Surgery
- Growth Hormone and Insulin-like Growth Factors
- Neuroblastoma Research and Treatments
- Adrenal Hormones and Disorders
- Body Contouring and Surgery
- Soft tissue tumor case studies
- Cancer Immunotherapy and Biomarkers
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
- Cancer-related Molecular Pathways
- Parathyroid Disorders and Treatments
- Renal Transplantation Outcomes and Treatments
- Nuclear Structure and Function
- Sarcoma Diagnosis and Treatment
Centre Hospitalier Universitaire de Lille
2016-2025
Université de Lille
2016-2025
Inserm
2020-2025
Hôpital Claude Huriez
2017-2025
Centre National de la Recherche Scientifique
2022-2024
CANTHER - Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers
2023-2024
Integrated Genomics and Metabolic Diseases Modeling
2020-2023
Onco Lille
2023
Université Lille Nord de France
2022
Lille’s Cardiology Hospital
2017
The evolutionary trajectories associated with demographic, genetic and spatial disequilibrium have become an issue of growing interest in population biology. Invasive species provide unique opportunities to explore the impact recent range expansion on life-history traits, making it possible test for a arrangement dispersal abilities along expanding range, particular. We carried out controlled experiments laboratory conditions hypothesis increase capacity Harmonia axyridis, ladybird that has...
OBJECTIVE The long-term outcome of allogenic islet transplantation is unknown. aim this study was to evaluate the 10-year in patients with type 1 diabetes and hypoglycemia unawareness and/or a functioning kidney graft. RESEARCH DESIGN AND METHODS We enrolled prospective parallel-arm cohort 28 subjects who received either alone (ITA) or after graft (IAK). Islet consisted two three intraportal infusions islets administered within (median [interquartile range]) 68 days (43–92)....
Abstract Context Germline CDKN1B variants predispose patients to multiple endocrine neoplasia type 4 (MEN4), a rare MEN1-like syndrome, with <100 reported cases since its discovery in 2006. Although mutations are frequently suggested explain of genetically negative MEN1, the prevalence and phenotype MEN4 is poorly known, genetic counseling unclear. Objective To evaluate MEN1-suspected characterize patients. Design Retrospective observational nationwide study. Narrative review...
A 29-y-old woman requiring total thyroidectomy with lymph node dissection for a stage pT3(m)N1bMxR2 solid variant of papillary thyroid cancer had, near the left recurrent vagal nerve, 16 × 10 8 mm cervical tumor residue deemed unresectable by expert surgeons. After hormone withdrawal, she
Background: Thermal ablation is a minimally invasive technique that gradually acknowledged as an effective alternative to surgery treat thyroid nodules. Two main techniques have been described: radiofrequency (RFA) and laser ablation.Objective: To evaluate the safety efficacy of two (RFA ablation) for treatment benign nodules.Patients: This bicentric retrospective study included 166 consecutive patients, who received clinical, biological ultrasound evaluations nodules, from October 2013...
Background: Lymph node dissection (LND) in primary treatment of differentiated thyroid carcinoma is controversial. The aim our retrospective study was to analyse the risk factors post-thyroidectomy complications and assess morbidity lymph dissection, especially central neck compartment, since prophylactic has not been proven bring an overall survival benefit. Methods: We performed a analysis postoperative from 1547 consecutive patients with academic department endocrine surgery over period...
Abstract Objective Metabolic flexibility, a key hallmark of cancer, reflects aberrant tumor changes associated with metabolites. The metabolic plasticity pancreatic neuroendocrine tumors (pNETs) remains largely unexplored. Notably, the heterogeneity pNETs complicates their diagnosis, prognosis, and therapeutic management. Here, we compared plasma metabolomic profiles patients pNET non-cancerous individuals to understand dysregulation. Design methods Plasma 76 38 were analysed using LC-MS/MS...
Background: Anaplastic thyroid carcinoma (ATC) is a rare and frequently fatal type of cancer. The degree heterogeneity in survival rates for ATC incompletely studied. This study evaluated the factors associated with overall (OS) patients using multicenter real-world data from national tertiary care center network France. Methods: In this multicenter, retrospective cohort study, all diagnosed between 2010 2020 were identified database French ENDOCAN-TUTHYREF network. Factors OS examined...
Abstract Cellular stress response contributes to epithelial defense in adaptation environment changes. Galectins play a pivotal role the regulation of this malignant cells. However, precise underlying mechanisms are largely unknown. Here we demonstrate that Galectin-3, pro and anti-apoptotic lectin, is required for setting up correct cellular by orchestrating several effects. First, Galectin-3 constitutes key post-transcriptional regulator stress-related mRNA regulons coordinating cell...
Abstract Purpose Bone metastases (BM) from differentiated thyroid carcinoma (DTC) impact negatively the quality of life and expectancy patients. The aim study was (a) to evaluate overall survival (OS) prognostic factors OS (b) assess predictive complete BM response (C-BM-R) using radioiodine treatment (RAI) either alone or in association with focal modalities. Methods A total 178 consecutive DTC patients harbouring BM, treated between 1989 2015, were enrolled this retrospective conducted two...
In allogenic islet transplantation (IT), high purity of preparations and low contamination by nonislet cells are generally favored. The aim the present study was to analyze relation between transplanted graft function during 5 years post-IT. Twenty-four patients with type 1 diabetes, followed for after IT, were enrolled. Metabolic parameters daily insulin requirements compared who received a mean <50% (LOW purity) or ≥50% (HIGH purity). We also analyzed blood levels carbohydrate antigen 19-9...
no abstract needed
Lipomatoses are benign proliferation of adipose tissue. Lipomas (benign fat tumors) the most common component lipomatosis. They may be unique or multiple, encapsulated not, subcutaneous sometimes visceral. In some cases, they form large areas non-encapsulated hypertrophy, with a variable degree fibrosis. can develop despite absence obesity. familial acquired. At difference lipodystrophy syndromes, not associated lipoatrophy areas, except in rare cases such as type 2 partial syndromes...
Abstract Context In patients with neurofibromatosis type 1 (NF1), guidelines suggest screening for pheochromocytoma by metanephrine measurement and abdominal imaging, which may lead to the discovery of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) their differential diagnosis, gastrointestinal stromal (GISTs). Other endocrine manifestations such as follicular thyroid carcinoma primary hyperparathyroidism have also been reported in a few cases. Objective This study aimed describe...