A5089639127- Hepatocellular Carcinoma Treatment and Prognosis
- Management of metastatic bone disease
- Medical Imaging and Pathology Studies
- Occupational Health and Safety Research
- Cancer Genomics and Diagnostics
- Spinal Fractures and Fixation Techniques
- Lung Cancer Treatments and Mutations
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Occupational exposure and asthma
- Spine and Intervertebral Disc Pathology
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Bone health and treatments
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Pituitary Gland Disorders and Treatments
- Renal cell carcinoma treatment
- Occupational and environmental lung diseases
- Cancer, Hypoxia, and Metabolism
- Advanced Radiotherapy Techniques
- Musculoskeletal pain and rehabilitation
- Air Quality and Health Impacts
Institut Gustave Roussy
2016-2025
Université Paris-Saclay
2016-2025
Centre National de la Recherche Scientifique
2023-2025
Université de Reims Champagne-Ardenne
2012-2024
Centre Hospitalier Universitaire de Reims
2011-2024
Inserm
2015-2024
École Supérieure de Psychologie
2024
Society of Interventional Radiology
2023
Bicêtre Hospital
2015-2022
Imagerie Adaptative Diagnostique et Interventionnelle
2013-2022
High-throughput genomic analyses may improve outcomes in patients with advanced cancers. MOSCATO 01 is a prospective clinical trial evaluating the benefit of this approach. Nucleic acids were extracted from fresh-frozen tumor biopsies and analyzed by array comparative hybridization, next-generation sequencing, RNA sequencing. The primary objective was to evaluate as measured percentage presenting progression-free survival (PFS) on matched therapy (PFS2) 1.3-fold longer than PFS prior (PFS1)....
Clinicians increasingly require short, efficient methods for assessing distress, both in applied research and clinical settings. Most of the available questionnaires are unsuitable busy The visual analogue scale (VAS) is widely but empirically used to assess perceived stress. To provide evidence on two psychometric properties VAS: its discriminative sensitivity (capacity highlight a difference between groups) interconcept validity (the relationship VAS stress assessment different, similar...
Minimal invasive methods are needed as an alternative to surgery for treatment of lung metastases.The prospective database two cancer centers including all consecutive patients treated with radiofrequency ablation (RFA) metastasis over 8 years was reviewed. RFA carried out under general anesthesia, computed tomography guidance using a 15-gauge multitined expandable electrodes RF needle.Five hundred sixty-six 290 men (51%), 62.7 ± 13.2 old primary tumor the colon (34%), rectum (18%), kidney...
Abstract
Cyclophosphamide–dacarbazine–vincristine regimen is recommended for the treatment of malignant pheochromocytoma and paraganglioma (MPP); however, dacarbazine only recognized active drug in neuroendocrine tumours. We investigated therapeutic benefit temozolomide (TMZ), an oral alternative to dacarbazine, patients with MPP. This a retrospective study consecutive documented progressive examined correlation between Succinate dehydrogenase B ( SDHB ) mutation O(6)‐methylguanine‐DNA...
In patients with liver malignancies potentially amenable to curative extended right hepatectomy but insufficient size of the future remnant (FLR), portal vein embolization (PVE) tumor-bearing is used induce contralateral hypertrophy leaves tumor untreated. Radioembolization (RE) treats in embolized lobe along induction. We performed a matched-pair analysis compare capacity for induction these two modalities. Patients right-hepatic secondary no or negligible left-hepatic involvement who were...
<h3>Introduction</h3> To assess the feasibility, safety and local tumor control of cryoablation for treatment pulmonary metastases. <h3>Materials Methods</h3> This Health Insurance Portability Accountability Act (HIPAA) compliant, IRB-approved, multicenter, prospective, single arm study included 40 patients with 60 lung metastases treated during 48 sessions, currently a minimum 12 months follow-up. Patients were enrolled according to following key inclusion criteria: 1 5 from extrapulmonary...
Abstract Purpose: This single-institutional feasibility study prospectively characterized genomic alterations in recurrent or refractory solid tumors of pediatric patients to select a targeted therapy. Experimental Design: Following treatment failure, with signed consent and ages above 6 months, underwent tumor biopsy surgical resection primary metastatic site. These newly acquired samples were analyzed by comparative hybridization array, next-generation sequencing for 75 target genes,...
To assess the feasibility and safety of a robotic system for percutaneous needle insertion during thermal ablation liver tumors. This study analyzed CT-guided using EPIONE device (Quantum Surgical, Montpellier, France) radiofrequency or microwave ablation. The main criteria were (possibility to perform after insertion), number adjustments (reiteration robotically assisted when initial positioning is considered insufficient ablation), robotic-guided procedure (complications related...
Robotic assistance is rapidly evolving and may help physicians optimize needle guidance during percutaneous interventions. The purpose of the study was to report feasibility, safety, accuracy, immediate clinical success short-term local tumor control after robotic-assisted computed tomography (CT)-guided thermal ablation abdominal tumors.
The purpose of this study was to evaluate computed analysis three-dimensional (3D) cone-beam tomography angiography (CTA) the liver for determination subsegmental tumor-feeding vessels (FVs). Eighteen consecutive patients underwent transarterial chemoembolization (TACE) from January October 2008 25 tumors (15 hepatocellular carcinomas [HCCs] and 10 neuroendocrine metastases). Anteroposterior projection angiogram (two-dimensional [2D]) 3D CTA images were acquired by injection common hepatic...
To compare fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with computed (PET/CT) and chest CT in the evaluation of effectiveness lung radiofrequency (RF) ablation.Institutional review board approved study, all patients gave written informed consent. Thirty-four (22 men 12 women; mean age, 64 years) planned to undergo RF ablation were prospectively included underwent FDG PET/CT before (pre-RF PET) 24 hours, 1 month, 3 months after ablation. Persistent...