A5030331048- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Medical Imaging and Pathology Studies
- MRI in cancer diagnosis
- Lymphoma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Lung Cancer Treatments and Mutations
- Pancreatic and Hepatic Oncology Research
- Glioma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- Radiation Dose and Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Functional Brain Connectivity Studies
- Colorectal Cancer Treatments and Studies
- Renal cell carcinoma treatment
- Cardiac Imaging and Diagnostics
Charité - Universitätsmedizin Berlin
2016-2025
Humboldt-Universität zu Berlin
2004-2025
Freie Universität Berlin
2004-2025
Klinik und Poliklinik für Nuklearmedizin
2013-2025
University Hospital Magdeburg
2012-2023
Otto-von-Guericke University Magdeburg
2009-2023
Max Delbrück Center
2022-2023
KU Leuven
2023
Auguste-Viktoria-Klinik
2022
Society of Interventional Radiology
2016-2022
The objective of this study was to evaluate the impact positron emission tomography (PET) using fluorine-18-fluorodeoxyglucose (FDG) for initial staging and therapy planning in pediatric sarcoma patients.In prospective multicenter study, 46 patients (females, n = 22; males, 24; age range, 1 18 years) with histologically proven (Ewing family tumors, 23; osteosarcoma, 11; rhabdomyosarcoma, 12) were examined conventional imaging modalities (CIMs), including ultrasound, computed (CT), magnetic...
In patients with liver malignancies potentially amenable to curative extended right hepatectomy but insufficient size of the future remnant (FLR), portal vein embolization (PVE) tumor-bearing is used induce contralateral hypertrophy leaves tumor untreated. Radioembolization (RE) treats in embolized lobe along induction. We performed a matched-pair analysis compare capacity for induction these two modalities. Patients right-hepatic secondary no or negligible left-hepatic involvement who were...
Purpose In adult Hodgkin's lymphoma (HL) risk stratification after early therapy response assessment with [ 18 F]fluorodeoxyglucose (FDG) positron emission tomography (PET) seems to allow tailoring less toxicity for patients adequate metabolic response. This study delivers the first prospective data on potential of FDG-PET in pediatric HL. Patients and Methods was performed 40 HL before polychemotherapy (PET-1), two cycles (PET-2), completion (PET-3). Mean follow-up 46 months (range, 26 72...
<i>Aim:</i> Retrospective evaluation of the impact integrated positron emission tomography/computed tomography (PET/CT) using <sup>68</sup>Ga-DOTA(0)-Phe(1)-Tyr(3)-octreotide (<sup>68</sup>Ga-DOTATOC) on therapeutic management patients with neuroendocrine tumors (NET). <i>Methods:</i> The <sup>68</sup>Ga-DOTATOC-PET/CT data 66 (31 male, 35 female; age: 29–79, mean 56 years) known or suspected NET were included. Imaging (PET and...
Purpose Currently, a routine bone marrow biopsy (BMB) is performed to detect (BM) involvement in pediatric Hodgkin's lymphoma (HL) stage greater than IIA. [ 18 F]fluorodeoxyglucose positron emission tomography (FDG-PET) increasingly used for the initial staging of HL. The value using FDG-PET BM has not been sufficiently defined. We compared results BMBs and diagnosis large group with Patients Methods 175 patients newly diagnosed classical HL IIA was determined by BMB, FDG-PET, chest computed...
JAK2-V617F–positive chronic myeloproliferative neoplasia (CMN) commonly displays dysfunction of integrins and adhesion molecules expressed on platelets, erythrocytes, leukocytes. However, the mechanism by which 2 major leukocyte integrin chains, β1 β2, may contribute to CMN pathophysiology remained unclear. (α4β1; VLA-4) β2 (αLβ2; LFA-1) are essential regulators for attachment leukocytes endothelial cells. We here showed enhanced granulocytes from mice with JAK2-V617F knockin (JAK2+/VF mice)...
We evaluated whether the artificial intelligence chatbot ChatGPT can adequately answer patient questions related to [<sup>18</sup>F]FDG PET/CT in common clinical indications before and after scanning. <b>Methods:</b> Thirteen regarding were submitted ChatGPT. was also asked explain 6 reports (lung cancer, Hodgkin lymphoma) follow-up (e.g., on tumor stage or recommended treatment). To be rated "useful" "appropriate," a response had adequate by standards of nuclear medicine staff....
PURPOSE: To prospectively assess accuracy of magnetic resonance (MR) imaging, MR cholangiopancreatography (MRCP), and angiography in patients suspected having pancreatic tumors. MATERIALS AND METHODS: Sixty-six tumors underwent imaging (unenhanced contrast material–enhanced MR, MRCP, contrast-enhanced angiography). Two blinded readers analyzed the images by consensus, results were correlated with surgery, biopsy, or follow-up findings. Results tabulated two-by-two tables. RESULTS: assessment...
To determine the value of single photon emission computed tomography (SPECT) with integrated low-dose (CT) for interpretation inconclusive foci in planar I whole-body scans after radioiodine therapy.Twenty-five patients findings scanning ablative therapy (3.7 GBq I) due to differentiated thyroid cancer were included. SPECT/CT region question was performed Millennium VG Hawkeye (GE Medical Systems). SPECT and without CT fusion evaluated by two blinded independent nuclear medicine physicians a...
The diagnostic value of neuroendocrine tumor (NET) imaging using PET with integrated CT is dependent on both components. This retrospective study assessed the single phases a triple-phase (early arterial, portal-venous inflow, and venous) protocol in comparison to (68)Ga-DOTATOC masked reading.(68)Ga-DOTATOC PET/CT examinations from 51 patients known or suspected NET were included. Two readers data each 3 for lesions independently (using 3-point score: 1 = benign, 2 indeterminate, malignant)...
<sup>90</sup>Y radioembolization is a promising therapy for patients with primary and secondary liver malignancies. Pretherapeutic assessment consists of hepatic angiography <sup>99m</sup>Tc-macroaggregated albumin (<sup>99m</sup>Tc-MAA) perfusion scintigraphy to estimate the liver-to-lung shunt exclude extrahepatic <sup>99m</sup>Tc-MAA deposition. However, predictive value intratumoral uptake remains unclear. <b>Methods:</b> One hundred four chemotherapy-refractory liver-dominant metastatic...