A5044167433- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Infrared Thermography in Medicine
- Tea Polyphenols and Effects
- Tannin, Tannase and Anticancer Activities
- Advanced Nanomaterials in Catalysis
- Nanoplatforms for cancer theranostics
- Thermoregulation and physiological responses
- Venous Thromboembolism Diagnosis and Management
Fujian Normal University
2021-2024
Photodynamic therapy (PDT) has been increasingly used in the clinical treatment of neoplastic, inflammatory and infectious skin diseases. However, generation reactive oxygen species (ROS) may induce undesired side effects normal tissue surrounding lesion, which is a big challenge for application PDT. To date, (–)-Epigallocatechin gallate (EGCG) widely proposed as an antiangiogenic antitumor agent protection from ROS-mediated oxidative damage. This study evaluates regulation ability EGCG...
Laser Speckle Contrast Imaging (LSCI) as the advantages of high speed, wide field view, and ease implementation has been widely used for imaging blood flow vascular deformation during Vascular targeted Photodynamic Therapy (V-PDT). However, uncorrected direction or scale kernel failed to improve visualization vessels derived from poor Signal Noise Ratio (SNR) micro V-PDT. In this study, we extracted adaptive directional using dual-wavelength reflection enhance laser speckle imaging. The in...
(-)-Epigallocatechin gallate (EGCG) has been widely proposed to treat as an antiangiogenic and antitumor agent for protection of healthy cells from reactive oxygen species mediated oxidative damage. In this study, the regulation ability EGCG photodynamic damage blood vessels was evaluated during vascular-targeted therapy (V-PDT) by using hematoporphyrin monomethyl ether (Hemoporfin). The quenching rate constants triplet-state Hemoporfin photosensitized 1O2 generation are 6.8 x108 M-1S-1 1.5...
Vascular-targeted photodynamic therapy (V-PDT) offers great promise as a treatment modality for vascular-related diseases. The injury of targeted blood vessels correlates to the singlet oxygen generation, which is affected by dosimetric parameters, including photosensitizer concentration, hemoglobin oxygenation and flow velocity. In this study, we developed an optical imaging system that combining hyperspectral (HSI), dual-wavelength reflection (DWRI) (λ<sub>1</sub> = 500 nm...