Yi Shen

ORCID: 0000-0003-4841-7561
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About
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Research Areas
  • Microtubule and mitosis dynamics
  • DNA Repair Mechanisms
  • Crystallography and molecular interactions
  • X-ray Diffraction in Crystallography
  • Mitochondrial Function and Pathology
  • Crystallization and Solubility Studies
  • Metal-Organic Frameworks: Synthesis and Applications
  • Microbial Community Ecology and Physiology
  • Photosynthetic Processes and Mechanisms
  • Genomics and Chromatin Dynamics
  • Soil Carbon and Nitrogen Dynamics
  • Enhanced Oil Recovery Techniques
  • Metal complexes synthesis and properties
  • Nanoplatforms for cancer theranostics
  • Colorectal Cancer Treatments and Studies
  • Hydrocarbon exploration and reservoir analysis
  • Medical Imaging and Pathology Studies
  • Chromosomal and Genetic Variations
  • Melanoma and MAPK Pathways
  • Pickering emulsions and particle stabilization
  • Genomics and Phylogenetic Studies
  • thermodynamics and calorimetric analyses
  • Cutaneous Melanoma Detection and Management
  • Chemical and Physical Properties in Aqueous Solutions
  • Magnetism in coordination complexes

State Key Laboratory of Plant Genomics
2023-2024

Institute of Genetics and Developmental Biology
2023-2024

Chinese Academy of Sciences
2007-2024

Nanjing General Hospital of Nanjing Military Command
2024

Northeast Petroleum University
2023-2024

Nanjing University
2024

Nanjing Agricultural University
2024

Fujian Normal University
2024

Wenzhou University
2013-2014

Institute of Hydrobiology
2007

Mosaic soil-landscapes with varying landforms and land covers are common in hilly areas of the lower Yangtze Valley China. Soil-health variations, primarily driven by soil organic matter (SOM) aggregation, across these affect agro-industrial development rural areas. Macroaggregates, through their pore structure, SOM storage microbial community habitat, variation among soil-landscape remains unaddressed. In this study, undisturbed topsoils (0–15 cm) were collected from forestland (FL) on...

10.1016/j.catena.2024.108056 article EN cc-by-nc CATENA 2024-05-08

Low permeability reservoirs are characterized by low permeability, small pore throat, strong heterogeneity, and poor injection-production ability. High shale content of the reservoir, pressure sensitivity, micropore undersaturation, significant water-lock effect in water injection development lead to increased fluid seepage resistance. There is an urgent need adopt physical chemical methods supplement energy improve infiltration efficiency, thereby forming effective for increasing production...

10.1021/acsomega.3c02853 article EN cc-by-nc-nd ACS Omega 2023-10-13

Photodynamic therapy (PDT) has been increasingly used in the clinical treatment of neoplastic, inflammatory and infectious skin diseases. However, generation reactive oxygen species (ROS) may induce undesired side effects normal tissue surrounding lesion, which is a big challenge for application PDT. To date, (–)-Epigallocatechin gallate (EGCG) widely proposed as an antiangiogenic antitumor agent protection from ROS-mediated oxidative damage. This study evaluates regulation ability EGCG...

10.1142/s1793545824500020 article EN cc-by Journal of Innovative Optical Health Sciences 2024-02-03

As an important means to enhance oil recovery, ternary composite flooding (ASP for short) technology has achieved remarkable results in Daqing Oilfield. Alkalis, surfactants and polymers are mixed specific proportions injected into the reservoir give full play synergistic effect of each component, which can effectively fluidity crude greatly improve recovery. At present, further improving recovery after is not mature belongs stage technical exploration. The presence alkaline substances...

10.3390/gels10080532 article EN cc-by Gels 2024-08-13

Abstract Centromeres consist of highly repetitive sequences that are challenging to map, clone, and sequence. Active genes exist in centromeric regions, but their biological functions difficult explore owing extreme suppression recombination these regions. In this study, we used the CRISPR/Cas9 system knock out transcribed gene Mitochondrial Ribosomal Protein L15 (OsMRPL15), located region rice (Oryza sativa) chromosome 8, resulting gametophyte sterility. Osmrpl15 pollen was completely...

10.1093/plphys/kiad153 article EN PLANT PHYSIOLOGY 2023-03-11

Abstract Background: The implementation of the multi-cancer early detection (MCED) test offers a valuable adjunct to existing screening methods, enabling more efficient cancer and potentially leading improved treatment outcomes prognoses for patients. Here, we report on performance an MCED test, which utilizes plasma cfDNA leverages genome-wide fragmentomics-based characteristics identify signals predict signal origin across diverse range types. Methods: Plasma from evaluable blood samples...

10.1158/1538-7445.am2024-1266 article EN Cancer Research 2024-03-22

Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete sterility,...

10.7554/elife.94180.2 preprint EN 2024-05-16

Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete sterility,...

10.7554/elife.94180.3 article EN cc-by eLife 2024-06-12

Mosaic soil-landscapes with varying landforms and land covers are common in hilly areas of the lower Yangtze Valley China. Soil-health variations, primarily driven by soil organic matter (SOM) aggregation, across these affect agro-industrial development rural areas. Macroaggregates, through their pore structure, SOM storage microbial community habitat, variation among soil-landscape remains unaddressed. In this study, undisturbed topsoils (0-15 cm) were collected from forestland (FL) on...

10.2139/ssrn.4621327 preprint EN 2023-01-01
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