A5051319755- DNA Repair Mechanisms
- Microtubule and mitosis dynamics
- Mitochondrial Function and Pathology
- Genomics and Chromatin Dynamics
- Plant Genetic and Mutation Studies
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Chromosomal and Genetic Variations
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- RNA Research and Splicing
State Key Laboratory of Plant Genomics
2021-2024
Chinese Academy of Sciences
2021-2024
Institute of Genetics and Developmental Biology
2021-2024
University of Chinese Academy of Sciences
2024
Yangzhou University
2024
National Cancer Institute
2024
Abstract Temperature is one of the key environmental factors influencing crop fertility and yield. Understanding how plants sense respond to temperature changes is, therefore, crucial for improving agricultural production. In this study, we characterized a temperature-sensitive male sterile mutant in rice (Oryza sativa), glutamyl-tRNA synthetase 1-2 (ers1-2), that shows reduced at high temperatures restored low temperatures. Mutation ERS1 resulted severely delayed pollen development meiotic...
Synaptonemal complex (SC) assembly and homologous recombination, the most critical events during prophase I, are prerequisite for faithful meiotic chromosome segregation. However, underlying regulatory mechanism remains largely unknown. Here, we reveal that a functional RING finger E3 ubiquitin ligase, DESYNAPSIS1 (DSNP1), plays significant roles in SC recombination rice meiosis. In dsnp1 mutant, synapsis is discontinuous aberrant SC-like polycomplexes occur independent of coaligned...
In flowering plants, the transition from mitosis to meiosis is precondition for gametogenesis, which most crucial event during sexual reproduction. Here, we report an intriguing mechanism whereby germ cells and surrounding somatic cooperatively involve in meiotic switch anther development rice (Oryza sativa). double mutants with loss function of both leptotene chromosome establishment- cell layer differentiation-associated genes, morphology reproductive remains same as that cells,...
Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete sterility,...
The transition from mitosis to meiosis is a critical event in the reproductive development of all sexually reproducing species. However, mechanisms that regulate this process plants remain largely unknown. Here, we find rice (Oryza sativa L.) protein RETINOBLASTOMA RELATED 1 (RBR1) essential meiosis. Loss RBR1 function results hyper-proliferative sporogenous-cell-like cells (SCLs) anther locules during early stages development. These SCLs are unable initiate meiosis, eventually stagnating...
Cohesin is a multi-subunit protein responsible for holding sister chromatids together during mitosis and meiosis. Each subunit functionally essential, their deletion always lethal. SCC3 highly conserved constituent of the cohesin complex. However, exact mitotic meiotic functions in rice remains to be elucidated. Here, we found null alleles cause embryo lethality. Only scc3 weak mutants could survive show vegetative reproductive defects. Specifically, replication process disturbed interphase...
Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete sterility,...
Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete sterility,...
Abstract Cohesin is a multi-subunit protein that plays pivotal role in holding sister chromatids together during cell division. Sister chromatid cohesion 3 (SCC3), constituents of cohesin complex, highly conserved from yeast to mammals. Since the deletion individual subunit always causes lethality, it difficult dissect its biological function both mitosis and meiosis. Here, we obtained scc3 weak mutants using CRISPR-Cas9 system explore rice The displayed obvious vegetative defects complete...