About
Contact & Profiles
Research Areas
- Atherosclerosis and Cardiovascular Diseases
- Aortic Disease and Treatment Approaches
- MicroRNA in disease regulation
- Aortic aneurysm repair treatments
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Sun Yat-sen University
2024
The mechanism by which aging induces aortic aneurysm and dissection (AAD) remains unclear. A total of 430 participants were recruited for the screening differentially expressed plasma microRNAs (miRNAs). We found that miR-1204 is significantly increased in both aorta elder patients with AAD positively correlated age. Cell senescence expression through p53 interaction plasmacytoma variant translocation 1, vascular smooth muscle cell (VSMC) to form a positive feedback loop. Furthermore,...
10.1038/s41467-024-50036-2
article
EN
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Nature Communications
2024-07-16
10.1016/s1567-5688(06)80757-9
article
EN
Atherosclerosis Supplements
2006-01-01
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