Yu-Jia Liu

ORCID: 0009-0008-2851-4675
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About
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Research Areas
  • Atherosclerosis and Cardiovascular Diseases
  • Aortic Disease and Treatment Approaches
  • MicroRNA in disease regulation
  • Aortic aneurysm repair treatments

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Sun Yat-sen University
2024

The mechanism by which aging induces aortic aneurysm and dissection (AAD) remains unclear. A total of 430 participants were recruited for the screening differentially expressed plasma microRNAs (miRNAs). We found that miR-1204 is significantly increased in both aorta elder patients with AAD positively correlated age. Cell senescence expression through p53 interaction plasmacytoma variant translocation 1, vascular smooth muscle cell (VSMC) to form a positive feedback loop. Furthermore,...

10.1038/s41467-024-50036-2 article EN cc-by Nature Communications 2024-07-16
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