A5006001591- COVID-19 Clinical Research Studies
- MicroRNA in disease regulation
- Chaos-based Image/Signal Encryption
- Long-Term Effects of COVID-19
- Advanced Fiber Laser Technologies
- Advanced Fiber Optic Sensors
- Thermal Regulation in Medicine
- Interactive and Immersive Displays
- Extracellular vesicles in disease
- Circular RNAs in diseases
- Optical Network Technologies
- COVID-19 and healthcare impacts
- Inflammasome and immune disorders
- Image and Video Stabilization
- Photonic and Optical Devices
- RNA modifications and cancer
- Diverticular Disease and Complications
- Vehicle emissions and performance
- Ultra-Wideband Communications Technology
- Image Processing and 3D Reconstruction
- Hand Gesture Recognition Systems
- SARS-CoV-2 and COVID-19 Research
- Tactile and Sensory Interactions
- Advanced Steganography and Watermarking Techniques
- Genomics, phytochemicals, and oxidative stress
Nanchang University
2025
The First Affiliated Hospital, Sun Yat-sen University
2022-2024
Sun Yat-sen University
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Wuhan University
2020-2023
Renmin Hospital of Wuhan University
2020-2023
China State Shipbuilding (China)
2021-2023
Chang'an University
2023
National Cheng Kung University
2023
South China Normal University
2022
Abstract Background A recently developing pneumonia caused by SARS-CoV-2 was originated in Wuhan, China, and has quickly spread across the world. We reported clinical characteristics of 82 death cases with COVID-19 a single center. Methods Clinical data on laboratory-confirmed as infection were obtained from Wuhan local hospital’s electronic medical records according to previously designed standardized collection forms. Results All patients residents great proportion them diagnosed severe...
The mechanism by which aging induces aortic aneurysm and dissection (AAD) remains unclear. A total of 430 participants were recruited for the screening differentially expressed plasma microRNAs (miRNAs). We found that miR-1204 is significantly increased in both aorta elder patients with AAD positively correlated age. Cell senescence expression through p53 interaction plasmacytoma variant translocation 1, vascular smooth muscle cell (VSMC) to form a positive feedback loop. Furthermore,...
The COVID-19 outbreak is becoming a public health emergency. Data are limited on the clinical characteristics and causes of death. A retrospective analysis deaths were performed for patients' characteristics, laboratory results, In total, 56 patients (72.7%) decedents (male–female ratio 51:26, mean age 71 ± 13, survival time 17.4 8.4 days) had comorbidities. Acute respiratory failure (ARF) sepsis main Increases in C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer lactic acid...
A highly general and straightforward approach to access chiral bis(indolyl)methanes (BIMs) bearing quaternary stereocenters has been realized
The substantial voids of porous pavement materials permit light and exhaust pollutants to infiltrate a considerable depth. Consequently, utilizing mixtures as carriers for photocatalytic enables greater exposure an environment conducive the degradation reaction. This study employed asphalt cement concrete pavements. Various amounts TiO2 were incorporated photocatalysts produce eco-friendly with capability. Based on self-developed apparatus methodology, its performance was evaluated under...
The efficacies of tricuspid valve repair, risk factors for treatment failure and postoperative quality life have not been thoroughly evaluated in patients with insufficiency associated rheumatic heart disease (RHD). We therefore reviewed our experience ring non-ring annuloplasty the functional (TI) RHD.
Colorectal cancer (CRC) is the third main cause of cancer-relevant deaths worldwide, and its incidence has increased in recent decades. Previous studies have indicated that certain long noncoding RNAs (lncRNAs) regulatory roles tumor occurrence progression. Often, lncRNAs are competitive endogenous sponge microRNAs to up-regulate mRNAs. Here, we examined role a novel lncRNA gamma-butyrobetaine hydroxylase 1 antisense RNA (BBOX1-AS1) CRC. We observed BBOX1-AS1 overexpressed CRC cell lines,...
Abstract Background As a natural alkaloid product isolated from Sophora alopecuroides. L , Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated macrophages (TAMs). However, the exact effects underlying mechanism on cells remains poorly known. Methods The potential anti-tumor cell lines, including AGS SGC7901 cells, were detected by CCK-8, EDU colony forming assay, immunofluorescence, transwell flow cytometry. Molecular...
Abstract Clinical data on coronavirus disease 2019 (COVID-19) with pancreatic injury are extremely limited. An acute manifestation of pancreatitis in COVID-19 has not been reported. We describe here 2 cases as the initial Wuhan, China. Patient 1 died despite maximal mechanical ventilatory support and circulation support, while patient was finally discharged after showing significant improvement. Low T cells peripheral blood may indicate a poor outcome.
Position intervention has been shown to improve oxygenation, but its role in non-invasively ventilated patients with severe COVID-19 not assessed. The objective of this study was investigate the efficacy early position on COVID-19.This a single-center, prospective observational consecutive managed provisional ICU at Renmin Hospital Wuhan University from 31 January 15 February 2020. Patients chest CT showing exudation or consolidation bilateral peripheral and posterior parts lungs were...
Image scrambling is one important method in image encryption field. By using some characteristics of chaos system, e.g. the sensitivity to initial conditions, parameter and pseudo-randomicity, this paper presents algorithm based on chaotic mapping. In order achieve an effect scrambling, each pair pixel points exchanged for all possible combinations. Compared other algorithms which are mapping, has advantages, simplicity design high efficiency. paper, methodology evaluating degree position...
Gastric cancer is a common lethal malignancy and causes great cancer-related mortality worldwide. MicroRNA (miR)-328-3p implicated in the progression of various human cancers; however, its role mechanism gastric remain unclear.Human cells were incubated with miR-328-3p mimic, inhibitor or matched negative control. Cell viability, colony formation, migrative invasive capacity, cell apoptosis oxidative stress measured. To clarify involvement nuclear factor-E2-related factor 2 (NRF2) kelch-like...
We aimed to compare the therapeutic effects of stereotactic aspiration and best medical management in patients who developed supratentorial hypertensive intracerebral haemorrhage (HICH) with a volume between 20 40 mL.
Introduction: Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan late 2019, controversy on use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids. Patient concerns: A 53-year-old woman from suffered with COVID-19. Diagnosis: The chest computed tomography scan was suggestive diagnosis confirmed by real-time reverse transcription polymerase chain reaction test...
Abstract Purpose: For the emerging pandemic Coronavirus Disease 2019 (COVID-19), no clear description on its deaths’ clinical characteristics and causes of death is available. Hence, this study analyzed 77 COVID-19 deaths, providing data support to further understand disease. Method: A retrospective analysis deaths in East Branch, Renmin Hospital Wuhan University from February 1 March 7, 2020 was performed characteristics, laboratory results, death, subgroup comparison. Results: Totally...
The coronavirus disease 2019 (COVID-19) outbreak has become a global health threat and will likely be one of the greatest challenges in near future. battle between clinicians COVID-19 may "protracted war."The objective this study was to investigate risk factors for in-hospital mortality patients with COVID-19, so as provide reference early diagnosis treatment.This retrospectively enrolled 118 diagnosed who were admitted Eastern District Renmin Hospital Wuhan University from February 04, 2020...
We report the clinical characteristics of, viral shedding duration in and contact tracing for asymptomatic carriers of SARS-CoV-2 Wuhan, China. The were relatively young (median age: 34.5 years). Chest computed tomography showed no abnormalities. nasopharyngeal swab was optimum specimen RNA testing. median 11.5 days. Notably, two months we reported nurses much longer than previously or usually thought. transmissibility by during studied period Wuhan appeared to be weak. Only one patient...
In multi-touch interactive systems, it is of great significance to distinguish which hand the user touching surface in real time. Left-right distinction essential for recognizing multi-finger gestures and further fully exploring potential bimanual interaction. However, left-right beyond capability most existing systems. this paper, we present a new method left right based on human anatomy, work area, finger orientation position. Considering ergonomics principles gesture designing,...