A5093842885- Analytical Chemistry and Chromatography
- Psychedelics and Drug Studies
- Natural product bioactivities and synthesis
- Alkaloids: synthesis and pharmacology
- Phytochemical Studies and Bioactivities
- Mass Spectrometry Techniques and Applications
- Chemical and Physical Properties in Aqueous Solutions
- Chemical synthesis and alkaloids
- Advanced Chemical Sensor Technologies
- Phase Equilibria and Thermodynamics
- Phytochemistry and Biological Activities
Charles University
2024-2025
University of Hradec Králové
2024
A comprehensive two-step supercritical extraction using green solvents allows the of non-polar and polar analytes within one run in two consecutive steps.
An activity-guided isolation study on the EtOH extract prepared from bulbs of Prospero autumnale yielded four new phenolic compounds, including a stilbenoid (1), homoisoflavonoid derivative (8), dimer (9), and an unprecedented homoisoflavone–stilbene heterodimer (10), together with six known (2–7) analogs. Their chemical structures were elucidated by spectroscopic analysis theoretical NMR ECD calculations. Compounds 9 10 are unique in their scaffolds. The vitro cytotoxic activity purified...
Complex analysis of plant extracts usually requires a combination several analytical approaches. Therefore, in this study, we developed holistic two-injection approach for extract analysis, which is carried out within one instrument without the need any manual intervention during analysis. Ultrahigh-performance supercritical fluid chromatography (UHPSFC) was employed 17 volatile terpenes on porous graphitic carbon column 7.5 min, followed by short diol where flavonoids, phenolic acids, and...
This phytochemical study presents the isolation of eight alkaloids from