A5020628573- Phytochemical Studies and Bioactivities
- Natural product bioactivities and synthesis
- Phytochemistry and Bioactive Compounds
- Phytochemistry and Biological Activities
- Seaweed-derived Bioactive Compounds
- Mycotoxins in Agriculture and Food
- Plant Growth Enhancement Techniques
- Marine and coastal plant biology
- Essential Oils and Antimicrobial Activity
- Chemical synthesis and alkaloids
- Marine Sponges and Natural Products
- Traditional and Medicinal Uses of Annonaceae
- Algal biology and biofuel production
- Traditional Chinese Medicine Analysis
- Phytochemicals and Antioxidant Activities
- Analytical Chemistry and Chromatography
- Plant biochemistry and biosynthesis
- Computational Drug Discovery Methods
- Plant Diversity and Evolution
- Echinoderm biology and ecology
- Hibiscus Plant Research Studies
- Plant Physiology and Cultivation Studies
- Potato Plant Research
- Cassava research and cyanide
- Phytochemical and Pharmacological Studies
University of Portsmouth
2012-2024
Czech Academy of Sciences, Institute of Analytical Chemistry
2015
University of Bradford
2004
Portsmouth College
1983-2000
Charles University
1997-1998
Cardiff University
1990
Universidad de Los Andes
1988
University of Manitoba
1965-1966
University of Nottingham
1963
Quercetin, a naturally occurring dietary flavonoid, is well known to ameliorate chronic diseases and aging processes in humans, its antiviral properties have been investigated numerous studies. In silico vitro studies demonstrated that quercetin can interfere with various stages of the coronavirus entry replication cycle such as PLpro, 3CLpro, NTPase/helicase. Due pleiotropic activities lack systemic toxicity, derivatives may represent target compounds be tested future clinical trials enrich...
Abstract In a trial conducted in 1974, foliar application of an aqueous seaweed extract known cytokinin activity produced significant increase the yield potatoes variety King Edward. A synthetic cytokinin, kinetin, also increases tubers both varieties Edward and Pentland Dell. There was close correlation between results from use kinetin equivalent activity, which suggests that effect due to its content. complementary 1975 with potatoes, were obtained again tuber yields through treatment...
In the continuation of our research on seaweeds, crude extracts 21 brown algae collected from south coast England and west Ireland were screened for in vitro trypanocidal, leishmanicidal antimycobacterial activities. Mammalian stages a small set parasitic protozoa; i.e. Trypanosoma brucei rhodesiense, T. cruzi Leishmania donovani, tubercle bacillus Mycobacterium tuberculosis used as test organisms. The also evaluated selectivity by testing mammalian cell line (L6 cells). Only four moderately...
Hesperidin and hesperetin are flavonoids that abundantly present as constituents of citrus fruits. These compounds have attracted attention several computational methods, mostly docking studies, shown hesperidin may bind to multiple regions severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (spike protein, angiotensin-converting enzyme 2, proteases). has a low binding energy, both with the SARS-CoV-2 “spike” protein responsible for internalization, also “PL pro ” “M transforming...
The increased use of natural product in the pharmaceutical industry has led to an increase demand for screening bioactive compounds marine algae. An important economic algae, through chemical composition analysis and their antioxidant activities were investigated this study. Chemical three algal samples from Chlorophyta Ulva lactuca (U), Phaeophyta Sargassum crassifolia (S) Rhodophyta Digenea simplex (D) was tested. Main components sugars (57.40–185.13 mg/g dry weight), uronic acids...
In the continuation of our search for natural sources antiprotozoal and antitubercular molecules, we have screened crude extracts four green marine algae (Cladophora rupestris, Codium fragile ssp. tomentosoides, Ulva intestinalis lactuca) collected from Dorset area England. Trypanosoma brucei rhodesiense, cruzi, Leishmania donovani Mycobacterium tuberculosis were used as test organisms in vitro assays. The selective toxicity was also determined toward mammalian skeletal myoblast (L6) cells....
Ascophyllum nodosum, and to a lesser extent, Laminaria digitata, L. hyperborea Fucus serratus, are marine algal species utilized in the commercial production of seaweed extracts used agriculture. Betaines have been shown be important constituents these extracts, but there appears no study made on whether variations betaine contents based either place or date collection. Samples each four were collected from widely separated areas at different times year. Also, case A. approximately monthly...