Dustin Mikolajetz

ORCID: 0009-0008-3642-7424
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About
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Research Areas
  • Parathyroid Disorders and Treatments
  • Magnesium in Health and Disease
  • Regulation of Appetite and Obesity
  • Vitamin D Research Studies
  • Neurological Disorders and Treatments

RWTH Aachen University
2025

Patients with chronic kidney disease (CKD) show a high risk of cardiovascular diseases, predominantly caused by accelerated vascular calcification. Vascular calcification is highly regulated process no current treatment. The vasoconstriction-inhibiting factor (VIF) peptide was recently discovered vasoregulatory properties, but information regarding has been described. In the present work, inhibitory effect VIF analysed in vitro smooth muscle cells (VSMCs), ex vivo rat aortic rings, as well...

10.1093/cvr/cvaf016 article EN cc-by-nc Cardiovascular Research 2025-02-18

Abstract Background and Aims Patients with chronic kidney disease (CKD), have an increased risk of cardiovascular due to the massively accelerated calcification they develop. Vascular is a highly regulated process mediated by different inducers inhibitors. Recently, peptide ‘vasoconstriction inhibiting factor’ (VIF) was isolated from bovine adrenal glands has been described as inhibitor angiotensin II-induced vasoconstriction. Angiotensin II inhibits calcium deposition, but VIF effect on...

10.1093/ndt/gfae069.669 article EN other-oa Nephrology Dialysis Transplantation 2024-05-01
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