Endalew Yaze Muluneh

ORCID: 0009-0008-5298-8889
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About
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • Nanoparticle-Based Drug Delivery

Addis Ababa Science and Technology University
2023

The major goal of this investigation was to prepare a drug delivery polymeric nanoparticles (NPs) from 5-fluorouracil (FU) that could be delivered intravenously and improve the therapeutic index FU. In order achieve this, interfacial deposition method used FU entrapped poly-(lactic-co-glycolic acid) (FU-PLGA-NPs). influence various experimental settings on effectiveness integration into NPs assessed. Our findings show technique organic phase ratio aqueous had greatest impact NPs. results...

10.1155/2023/2334675 article EN cc-by Bioinorganic Chemistry and Applications 2023-04-17
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