A5101954368- Optical Systems and Laser Technology
- Infrared Target Detection Methodologies
- Advanced Measurement and Detection Methods
- Lung Cancer Treatments and Mutations
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA modifications and cancer
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Network Traffic and Congestion Control
- Aeroelasticity and Vibration Control
- Adaptive optics and wavefront sensing
- Advanced optical system design
- Internet Traffic Analysis and Secure E-voting
- Network Security and Intrusion Detection
- Piezoelectric Actuators and Control
- Inertial Sensor and Navigation
- Cardiac Arrest and Resuscitation
- Software-Defined Networks and 5G
- Space Satellite Systems and Control
- Trauma and Emergency Care Studies
- Network Packet Processing and Optimization
- Composite Structure Analysis and Optimization
- Phase Change Materials Research
- Satellite Image Processing and Photogrammetry
- Energy Efficient Wireless Sensor Networks
- Epigenetics and DNA Methylation
Chinese University of Hong Kong, Shenzhen
2021-2025
Tokyo University of Agriculture and Technology
2016-2024
Wuhan University
2024
Northwestern University
2023-2024
Yanbian University
2009-2024
Yanbian University of Science and Technology
2020-2024
Shaanxi Science and Technology Department
2024
University of Nottingham Ningbo China
2024
Northwestern Memorial Hospital
2024
Ningbo University
2013-2023
Background and Purpose— The natural product baicalein is a specific inhibitor of 12/15-lipoxygenase, but it also has antioxidant properties. current study was designed to test if the neuroprotective properties are related its lipoxygenase inhibition. Methods— presence 12/15-lipoxygenase in ischemic mouse brain demonstrated by immunohistochemistry. A model transient middle cerebral artery occlusion used lipoxygenase-dependent protection baicalein. Rat primary neurons were subjected oxidative...
The closed-loop wireless power transfer (WPT) system can realize constant voltage output in the presence of perturbation. However, parameter design controller is a difficult problem. traditional trial-and-error method time-consuming and to find optimal parameters. A optimization strategy control systems for uncertain WPT using modified genetic algorithm (MGA) proposed. Firstly, because has different characteristics at periods, simulation process divided into three stages. first one start-up...
Future demographic changes predict an increase in the number of patients with atrial fibrillation. As long-term anticoagulation for prevention ischemic strokes becomes more prevalent, burden warfarin-associated intracerebral hemorrhage (W-ICH) is likely to grow. However, little known about clinical aspects and pathophysiologic mechanisms W-ICH. This study describes development a mouse model W-ICH which hematoma growth outcomes can be correlated parameters.CD-1 mice were treated warfarin (2...
Cornuside, a secoiridoid glucoside compound, was isolated from the fruit of Cornus officinalis SIEB. et ZUCC. Cornuside has been reported to possess immunomodulatory and anti-inflammatory activities. However, effects mechanism action cornuside in inflammation have not fully characterized. The present study therefore designed examine whether suppresses inflammatory response lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. significantly inhibited LPS-induced production nitric...
Traumatic brain injury (TBI) and hemorrhagic shock (HS) are the leading causes of trauma-related mortality morbidity. Combination TBI HS (TBI + HS) is highly lethal, optimal resuscitation strategy for this combined insult remains unclear. A critical limitation lack suitable large animal models to test different treatment strategies. We have developed a clinically relevant model HS, which was used evaluate impact treatments on lesion size associated edema. Yorkshire swine (42–50 kg) were...
Vascular endothelial growth factor (VEGF) is supposed to contribute the pathogenesis of allergic airway disease. VEGF expression regulated by a variety stimuli such as nitric oxide, factors, and hypoxia-inducible factor-1 alpha (HIF-1α). Recently, inhibition mammalian target rapamycin (mTOR) has been shown alleviate cardinal asthmatic features, including hyperresponsiveness, eosinophilic inflammation, increased vascular permeability in asthma models. Based on these observations, we have...
Traumatic brain injury (TBI) and hemorrhagic shock (HS) can be associated with coagulopathy inflammation, but the mechanisms are poorly understood. We hypothesized that a combination of TBI HS would disturb coagulation, damage endothelium, activate inflammatory complement systems.A total 33 swine were allocated to either + (n = 27, volume-controlled 40% blood loss) or controls 6, anesthesia instrumentation). animals left hypotensive (mean arterial pressure, 30-35 mm Hg) for 2 hours. Blood...
NAD(P)H:quinone oxidoreductase (NQO1) is a flavoprotein that catalyzes two-electron reduction and detoxification of quinones its derivatives. NQO1 reactions have protective effect against redox cycling, oxidative stress neoplasia. High expression associated with many solid tumors including those affecting the colon, breast pancreas; however, role in progression ovarian carcinoma largely undefined. This study aimed to investigate clinicopathological significance high serous carcinoma. protein...
Primary hepatic cancer (PHC) is a common malignant tumor and the third most frequent cause of cancer-related death worldwide. However, molecular mechanisms underlying remain unknown.
In Brief BACKGROUND We have previously demonstrated that valproic acid (VPA), a histone deacetylase inhibitor, can improve survival after hemorrhagic shock (HS), protect neurons from hypoxia-induced apoptosis, and attenuate the inflammatory response. also shown administration of 6% hetastarch (Hextend [Hex]) traumatic brain injury (TBI) decreases swelling, without affecting size lesion. This study was performed to determine whether addition VPA Hex would decrease lesion in clinically...
Traumatic brain injury (TBI) and hemorrhage are the leading causes of trauma-related mortality. Both TBI associated with coagulation disturbances, including platelet dysfunction. We hypothesized that dysfunction could be detected early after injury, this would activation, as measured by circulating levels activation markers.A total 33 swine were allocated to hypotension (n = 27, volume-controlled 40% blood loss) or controls 6, anesthesia instrumentation only). Animals in TBI/Hemorrhage group...
The DEK protein is related to chromatin reconstruction and gene transcription, plays an important role in cell apoptosis. High expression levels of the human have been correlated with numerous malignancies. This study explores roles tumor progression as a prognostic determinant colorectal cancer.Colorectal cancer specimens from 109 patients strict follow-up, adenomas 52 were selected for analysis by immunohistochemistry. correlations between over clinicopathological features cancers...
Abstract Diffractive deep neural networks (D 2 NN) have shown advantages in artificial intelligence image processing tasks, such as lens-free imaging. Since the accuracy and resolution of current fabrication technologies photolithography 3D printing are difficult to meet low-cost D NN manufacturing, order solve this problem, we designed height quantized diffractive networks, thereby improving detail reducing requirements. We experimentally verified functionality proposed simulation results...
This paper examines a continuous-time routing system with general interarrival and service time distributions, operating under either the join-the-shortest-queue policy or power-of-two-choices policy. Under weaker set of assumptions than those commonly established in literature, we prove that scaled steady-state queue length at each station converges weakly to common exponential random variable heavy traffic. Specifically, our results hold assumption (2 + ε)th moment for distributions some ε...
We establish uniform moment bounds for steady-state queue lengths of generalized Jackson networks (GJNs) in multiscale heavy traffic as recently proposed by Dai et al. 2023. Uniform lay the foundation further analysis limit stationary distribution. Our result can be used to verify crucial state space collapse (SSC) assumption 2023 a product-form GJN regime. proof critically utilizes Palm version basic adjoint relationship (BAR) developed Braverman 2024. Funding: X. Chen acknowledges support...