A5054040541- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Advanced Nanomaterials in Catalysis
- Electrochemical sensors and biosensors
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
- Molecular Sensors and Ion Detection
- RNA Interference and Gene Delivery
- Molecular Junctions and Nanostructures
- Alzheimer's disease research and treatments
- Conducting polymers and applications
- Metal-Organic Frameworks: Synthesis and Applications
- Analytical Chemistry and Sensors
- MXene and MAX Phase Materials
- SARS-CoV-2 detection and testing
- Semiconductor materials and devices
- Carbon and Quantum Dots Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Gas Sensing Nanomaterials and Sensors
- Quantum Dots Synthesis And Properties
- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
- Peptidase Inhibition and Analysis
- Mycotoxins in Agriculture and Food
Qilu Normal University
2024
University of Jinan
2017-2023
The successful use of electrochemiluminescence (ECL) in immunoassay for clinical diagnosis requires development novel ECL signal probes. Herein, we report lanthanide (Ln) metal–organic frameworks (LMOFs) as emitters the immunoassay. LMOFs were prepared from precursors containing Eu (III) ions and 5-boronoisophthalic acid (5-bop), which could be utilized to adjust optical properties. Investigations emission mechanisms revealed that 5-bop was excited with ultraviolet photons generate a...
We have proposed a dual-quenching electrochemiluminescence (ECL) strategy which is based on tris(2,2′-bipyridyl)ruthenium(II) [Ru(bpy)32+] as chromophores caged in three-dimensional (3D) zinc oxalate metal–organic frameworks [Ru(bpy)32+/zinc MOFs] for ultrasensitive detection of amyloid-β (Aβ). The chromophore connectivity MOFs provided network rapid excited-state energy transfer migration among Ru(bpy)32+ units shielded the from solvent molecules and led to high-energy Ru emission...
This work describes a sandwich-type electrochemiluminescence (ECL) strategy for insulin detection by using Ru(bpy)32+ as the luminophore which was encapsulated in UiO-67 metal–organic framework (UiO-67/Ru(bpy)32+). Because possesses characteristics of large specific surface area and porosity, more could be loaded onto its holes, thus greatly improving ECL efficiency. Furthermore, resonance energy transfer (ECL–RET) occur between UiO-67/Ru(bpy)32+ (ECL donor) Au@SiO2 nanoparticles acceptor),...
The successful application of electrochemiluminescence (ECL) in various fields required continuous exploration novel ECL signal emitters. In this work, we have proposed a pristine luminophor named NiRu MOFs, which owned extremely high and stable transmission efficiency was synthesized via straightforward two-step hydrothermal pathway. foundation framework pure Ni-MOFs with the initial structure layered-pillared constructed by coordinated octahedrally divalent between nickel terephthalic acid...
Improving the sensitivity and accuracy of bioimmunoassays has been focus research into development electrochemiluminescence (ECL) sensing platforms, as this is a critical factor in their application to practical analysis. In work, an electrochemiluminescence–electrochemistry (ECL–EC) dual-mode biosensing platform based on “off–on–super on” signals pattern strategy was developed for ultrasensitive detection Microcystin-LR (MC-LR). system, sulfur quantum dots (SQDs) are novel class ECL cathode...
In this work, an electrochemiluminescence (ECL) quenching system using multimetal–organic frameworks (MMOFs) was proposed for the sensitive and specific detection of heart-type fatty acid-binding protein (H-FABP), a marker acute myocardial infarction (AMI). Bimetallic MOFs containing Ru Mn as metal centers were synthesized via one-step hydrothermal method, yielding RuMn ECL emitter. The not only possessed strong performance Ru(bpy)32+ but also maintained high porosity original active sites...
In this study, a sensitive label-free electrochemical immunosensor was designed based on nanoporous Fe<sub>3</sub>O<sub>4</sub>and biotin–streptavidin system to specifically detect zearalenone (ZEN).
Here, a dual-mode quenched electrochemiluminescence (ECL) immunosensor based on PtPd@PDA was proposed. Among them, nitrogen-doped hydrazide conjugated carbon dots (NHCDs), as an ECL emitter and donor of resonance energy transfer, were by (receptor). At the same time, PDA in PtPd@PDA, oxygen radical scavenger, completed further quenching signal consuming O2•– generated decomposition co-reactant H2O2. The from above two channels achieved. In addition, compared with traditional quantum dots,...
The exploration of novel electrochemiluminescence (ECL) reagents has been a breakthrough work in ECL immunoassay. In this work, the properties polyoxomolybdate-zirconia (POM-ZrO2) were discovered for first time and their luminescence mechanism was initially explored. Virgulate POM-ZrO2 synthesized from phosphomolybdic acid hydrate zirconium oxychloride by solvothermal method, which achieved intense stabilized cathode emission at negative potential. Polyaniline@Au nanocrystals (PANI@AuNPs) as...
To ensure drinking water quality, the development of rapid and accurate analytical methods is essential. Herein, a highly sensitive electrochemiluminescence (ECL) aptasensor-based on signal on–off–on strategy was developed to detect pollutant microcystin-LR (MC-LR). This based newly prepared ruthenium-copper metal–organic framework (RuCu MOF) as ECL signal-transmitting probe three types PdPt alloy core–shell nanocrystals with different crystal structures signal-off probes. Compounding...
Neuron-specific enolase (NSE) has gained extensive attention as a reliable target for detecting small cell carcinoma of lungs. In this paper, an electrochemical immunoassay method based on molybdenum disulfide (MoS2) is proposed to detect NSE sensitively. By in-situ growth method, MoS2 and Au nanoclusters (Au NCs) were composited form MoS2@Au nanozyme, then the secondary antibodies modified. Primary immobilized amino-reduced graphene oxides capture NSE. The flower-like nanozyme provided...