- Transport and Logistics Innovations
- Industrial Technology and Control Systems
- Numerical methods in engineering
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Simulation and Modeling Applications
- Hepatitis C virus research
- Mathematical and Theoretical Epidemiology and Ecology Models
- Fatigue and fracture mechanics
- Spondyloarthritis Studies and Treatments
- Vehicle emissions and performance
- Machine Learning in Bioinformatics
- vaccines and immunoinformatics approaches
- Mechanical stress and fatigue analysis
- Technical Engine Diagnostics and Monitoring
- Immune Cell Function and Interaction
- Musculoskeletal pain and rehabilitation
- Gut microbiota and health
- Quantum chaos and dynamical systems
- Lymphoma Diagnosis and Treatment
- Advanced Sensor and Control Systems
- Autoimmune and Inflammatory Disorders Research
- Liver Disease Diagnosis and Treatment
Yanshan University
2024-2025
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Wenzhou Medical University
2024
Peking University
2023
Jiangsu University of Technology
2012
Background Observational studies have hinted at a correlation between the gut microbiota and spinal pain (SP). However, impact of on SP remains inconclusive. Methods In this study, we employed two-sample Mendelian randomization (MR) analysis to explore causal relationship SP, encompassing neck (NP), thoracic spine (TSP), low back (LBP), (BP). The compiled data originated from genome-wide association study (GWAS) conducted by MiBioGen consortium ( n = 18,340). Summary for NP were sourced UK...
Abstract Background Juvenile idiopathic arthritis (JIA) is a type of chronic childhood with complex pathogenesis. Immunological studies have shown that JIA an acquired self-inflammatory disease, involving variety immune cells, and it also affected by genetic environmental susceptibility. However, the precise causative relationship between phenotype cells remains unclear to date. The objective our study approach this inquiry from perspective, employing method association analysis ascertain...
The never-ending emergence of SARS-CoV-2 variations concern (VOCs) has challenged the whole world for pandemic control. In order to develop effective drugs and vaccines, one needs efficiently simulate spike receptor-binding domain (RBD) mutations identify high-risk variants. We pretrain a large protein language model with approximately 408 million sequences construct high-throughput screening prediction binding affinity antibody escape. As first work on RBD mutation simulation, we...
In this paper, a numerical analytical method for singularity problem in V-type notch is presented based on Hamiltonian system. The has an advantage that all boundary conditions can be considered with one model, and belongs to general method. Results show the of relates opening angle where crack just special case. Further, results give rules stress distribution under various conditions.