A5002143075- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Hybrid Renewable Energy Systems
- CRISPR and Genetic Engineering
- Integrated Energy Systems Optimization
- Viral Infections and Immunology Research
- Energy and Environment Impacts
University of California, San Diego
2023-2024
University of California, Berkeley
2018
Introns containing homing endonucleases are widespread in nature and have long been assumed to be selfish elements that provide no benefit the host organism. These genetic common viruses, but whether they confer a selective advantage is unclear. In this work, we studied intron-encoded endonuclease gp210 bacteriophage ΦPA3 found it contributes viral competition by interfering with replication of coinfecting phage, ΦKZ. We show targets specific sequence ΦKZ, which prevents assembly progeny...
Abstract Mobile introns containing homing endonucleases are widespread in nature and have long been assumed to be selfish elements that provide no benefit the host organism. These genetic common viruses, but whether they confer a selective advantage is unclear. Here we studied mobile intron bacteriophage ΦPA3 found its endonuclease gp210 contributes viral competition by interfering with virogenesis of co-infecting phage ΦKZ. We show targets specific sequence competitor ΦKZ, preventing...
There are over 600 million people without access to electricity in Sub-Saharan Africa. The design of sustainable systems needed fuel development the region requires context-specific power system modeling. Modeling data requirements however can be challenging for researchers and other stakeholders access. To address this, an open-access cost optimization capacity expansion model, known as PROGRESS (Programmable Resource Optimization Growth Renewable Energy Sustainable Systems), has been built...