Muhammad Bilal

ORCID: 0009-0008-7151-4275
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Research Areas
  • Spectroscopy and Chemometric Analyses
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Advanced Chemical Sensor Technologies
  • Identification and Quantification in Food
  • Edible Oils Quality and Analysis
  • Postharvest Quality and Shelf Life Management
  • Hepatitis B Virus Studies
  • Mosquito-borne diseases and control
  • Phytochemicals and Antioxidant Activities
  • Mycotoxins in Agriculture and Food
  • Hemoglobinopathies and Related Disorders
  • Asthma and respiratory diseases
  • Bee Products Chemical Analysis
  • Coconut Research and Applications
  • Listeria monocytogenes in Food Safety
  • Iron Metabolism and Disorders
  • Computational Drug Discovery Methods
  • MicroRNA in disease regulation
  • Hepatitis C virus research
  • Plant Pathogens and Fungal Diseases
  • Essential Oils and Antimicrobial Activity
  • Fractional Differential Equations Solutions
  • Horticultural and Viticultural Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Therapeutic Uses of Natural Elements

Nanjing Agricultural University
2023

Pakistan Institute of Engineering and Applied Sciences
2017-2023

Sligo University Hospital
2023

Allama Iqbal Medical College
2022

Jinnah Medical & Dental College
2020

Pakistan Institute of Nuclear Science and Technology
2015-2019

National Institute of Oceanography
2017

The current study presents the use of Raman spectroscopy combined with support vector machine (SVM) for classification dengue suspected human blood sera. spectra 84 clinically patients acquired from Holy Family Hospital, Rawalpindi, Pakistan, have been used in this study.The spectral differences between positive and normal sera exploited by using effective learning techniques. In regard, SVM models built on basis three different kernel functions including Gaussian radial function (RBF),...

10.1364/boe.7.002249 article EN cc-by Biomedical Optics Express 2016-05-18

Due to high price and nutritional values of extra virgin olive oil (EVOO), it is vulnerable adulteration internationally. Refined or other vegetable oils are commonly blended with EVOO unmask such fraud, quick, reliable technique needs be standardized developed. Therefore, in this study, edible (sunflower oil) made pure analyzed using fluorescence spectroscopy (excitation wavelength at 350 nm) conjunction principal component analysis (PCA) partial least squares (PLS) regression. Fluorescent...

10.1177/0003702818768485 article EN Applied Spectroscopy 2018-05-01

We present the optical diagnosis of dengue virus infection in human blood serum using Raman spectroscopy. spectra were acquired from 18 samples a laser at 532 nm as excitation source. A multivariate regression model based on partial least-squares is developed that uses to predict with leave-one-sample-out cross validation. The prediction by our yields correlation coefficient r2 values 0.9998 between predicted and reference clinical results. was tested for six unknown sera found be 100%...

10.1088/1612-2011/10/3/035602 article EN Laser Physics Letters 2013-01-18

We present the prediction of malaria infection in human plasma using Raman spectroscopy. spectra malaria-infected samples are compared with those healthy and dengue virus infected ones for disease recognition. were acquired a laser at 532 nm as an excitation source 10 distinct spectral signatures that statistically differentiated from dengue-infected cases found. A multivariate regression model has been developed utilized 20 malaria-infected, non-malarial fever, healthy, 6 to optically...

10.1117/1.jbo.20.1.017002 article EN Journal of Biomedical Optics 2015-01-14

The current study presents the application of fluorescence spectroscopy for identification cow and buffalo milk based on β-carotene vitamin-A which is prime importance from nutritional point view. All samples were collected healthy animals different breeds at time lactation in vicinity Islamabad, Pakistan. Cow shows differences emission appeared band position 382 nm, 440 505 nm 525 both classical geometry (right angle) setup as well front face setup. In geometry, synchronous clear 410...

10.1371/journal.pone.0178055 article EN cc-by PLoS ONE 2017-05-18

This work presents the evaluation of Raman spectroscopy using random forest (RF) for analysis dengue fever in infected human sera. A total 100 suspected blood samples, collected from Holy Family Hospital, Rawalpindi, Pakistan, have been used this study. Out these 45 were dengue-positive based on immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (ELISA) tests. For highlighting spectral differences between normal and an effective machine learning system is developed that...

10.1177/0003702817695571 article EN Applied Spectroscopy 2017-03-17

In this study, Raman spectroscopy together with chemometric techniques has been demonstrated to differentiate between cow and buffalo milk. The spectra of milk samples bovine contain peaks which show significant variation in intensity as well shift positions. outcome results indicates that successfully differentiates based on the presence absence β‐carotene, respectively. It also shows contains comparatively high fat (unsaturated/saturated) content. Principal component analysis‐based...

10.1002/jrs.5103 article EN Journal of Raman Spectroscopy 2017-02-10

Medical biophotonic tools provide new sources of diagnostic information regarding the state human health that are used in managing patient care. In our current study, Raman spectroscopy, together with chemometric technique, has successfully been demonstrated for screening asthma disease. spectra sera samples from asthmatic patients as well healthy (control) volunteers have recorded at 532 nm excitation. sera, three highly reproducible peaks assigned to β-carotene detected. Their sensitive...

10.1364/boe.10.000600 article EN cc-by Biomedical Optics Express 2019-01-16

The growth of the fusarium head blight (FHB) pathogen at grain formation stage is a deadly threat to wheat production through disruption photosynthetic processes spikes. Real-time nondestructive and frequent proxy detection approaches are necessary control propagation targeted fungicide application. Therefore, this study examined ch\lorophyll-related phenotypes or features from spectral chlorophyll fluorescence for FHB monitoring. A methodology developed using extracted hyperspectral...

10.3389/fpls.2022.1102341 article EN cc-by Frontiers in Plant Science 2023-01-16

The potential of fluorescence spectroscopy has been utilized to study the heating effects on extra virgin olive oil (EVOO). Through a series experiments, temperature range from 140 °C − 150 found where cooking with EVOO is possible without destroying its natural ingredients. Fluorescence emission spectra all heated and non-heated samples were recorded using an excitation source at 350 nm, bands in 380, 440, 455, 525 nm are labelled for vitamin E band 673 assigned chlorophyll a. also...

10.1088/1555-6611/aa8cd7 article EN Laser Physics 2017-11-13

This study presents differentiation in milk samples of mother's feeding male and female infants using Raman spectroscopy combined with a support vector machine (SVM).Major differences have been observed the spectra both types based on their chemical compositions.Overall, it has found that having infant are richer fatty acids, phospholipids, tryptophan.In contrast, contain more carotenoids saccharides.Principal component analysis SVM further highlighted between two groups basis...

10.1364/boe.9.000844 article EN cc-by Biomedical Optics Express 2018-01-26

This study demonstrates the analysis of nasopharyngeal cancer (NPC) in human blood sera using Raman spectroscopy combined with multivariate technique. Blood samples confirmed NPC patients and healthy individuals have been used this study. The spectra from all these were recorded 785 nm laser for excitation. Important bands at 760, 800, 815, 834, 855, 1003, 1220-1275, 1524 cm-1, observed both normal samples. A decrease lipids content, phenylalanine, β-carotene, whereas increases amide III,...

10.1177/0003702817723928 article EN Applied Spectroscopy 2017-07-20

Abstract The potential of Raman spectroscopy has been utilized for the diagnosis hepatitis B virus (HBV) infection in blood plasma. spectra 24 diseased and 10 healthy samples were used to develop distinct types support vector machine (SVM) models, including linear, quadratic, radial basis function (RBF) using multivariate method principal component analysis (PCA) reduce dimensions obtained datasets. To assess diagnostic power these algorithms, developed models tested on independent dataset....

10.1002/jrs.5896 article EN Journal of Raman Spectroscopy 2020-05-04

This work presents a diagnostic system for the hepatitis C infection using Raman spectroscopy and proximity based classification. The proposed method exploits transformed spectra machine learning technique is denoted as RS-PCA-Prox. First, spectral data baseline corrected by subtracting noise low intensity background. After this, feature transformation of adopted, not only to reduce feature's dimensionality but also learn different deviations in shifts. RS-PCA-Prox shows significant power...

10.1364/boe.9.002041 article EN cc-by Biomedical Optics Express 2018-04-03
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