A5056364995- Platelet Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Blood groups and transfusion
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hemophilia Treatment and Research
- Iron Metabolism and Disorders
- Blood disorders and treatments
- Blood donation and transfusion practices
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Respiratory viral infections research
- Ocular Diseases and Behçet’s Syndrome
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Antifungal resistance and susceptibility
- interferon and immune responses
- Testicular diseases and treatments
- Malaria Research and Control
- Bacterial Identification and Susceptibility Testing
- Eosinophilic Disorders and Syndromes
- Pancreatitis Pathology and Treatment
- Spectroscopy Techniques in Biomedical and Chemical Research
- Vasculitis and related conditions
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Sexual Differentiation and Disorders
Pakistan Atomic Energy Commission
2008-2023
Pakistan Institute of Medical Sciences
2017-2018
We present the prediction of malaria infection in human plasma using Raman spectroscopy. spectra malaria-infected samples are compared with those healthy and dengue virus infected ones for disease recognition. were acquired a laser at 532 nm as an excitation source 10 distinct spectral signatures that statistically differentiated from dengue-infected cases found. A multivariate regression model has been developed utilized 20 malaria-infected, non-malarial fever, healthy, 6 to optically...
Matched-related bone marrow transplantation (BMT) may cure >80% of low-risk children with severe thalassemia (ST). Very long-term follow-up studies have shown how the standard busulfan-cyclophosphamide (BuCy) regimen be associated normalization health-related quality life, no second malignancies in absence chronic graft-versus-host disease, and fertility preservation many patients. However, because BuCy high rejection rates, some centers incorporate thiotepa (Tt) busulfan- or...
Autosomal recessive bleeding disorders (ARBDs) include deficiencies of clotting factors I, II, V, VII, X, XI, XIII, vitamin K dependent factors, combined factor V & VIII, Von Willebrand Disease (vWD) type 3, Glanzmann's thrombasthenia (GT) and Bernard–Soulier syndrome. Patients with primary from all the major provincial capitals Pakistan were screened for ARBDs. Prothrombin (PT), activated partial thromboplastin time (APTT), (BT) fibrinogen levels measured. Cases isolated prolonged APTT...
Type 3 von Willebrand disease (VWD), a severe autosomal recessive hereditary bleeding disorder, is described by the virtual absence of factor (VWF). In consanguineous populations, for example Pakistan, reported with higher incidence rate than worldwide prevalence.This study aims to characterize molecular pathology and clinical profile type VWD cohort Pakistani origin.In total, 48 patients were enrolled in current study. Initially, index (IPs) evaluated standardized questionnaire recording...
A 22 years old primigravida presented with loose motion, fever and atonic seizures at home. Patient was markedly pale dehydrated. Her blood pressure 110/70 mmHg, temp 100F pulse 100/min. On obstetric examination baby corresponding to dates liquor adequate. complete count serum electrolytes were done. Platelet only 16,000/uL. admitted for evaluation management. Urgent hematological medical consultation done diagnosis of Thrombotic thrombocytopenic purpura made. put on steroids daily plasma...
Background: Glycopeptides have been used widely to treat methicillin resistant Staphylococcus aureus (MRSA) infections. Until recently vancomycin resistance among gram-positive bacteria had thought be uncommon but Glycopeptide intermediate S. (GISA) and heterogenous GISA (hGISA) reported from various parts of world. Strains hGISA MICs considered in the susceptible range (≤2.0 μg/ml) contain a subset bacterial population that expresses phenotype.This study has done evaluate current status...
Introduction: Retinoblastoma is most common pediatric ocular malignancy.Majority of patients presented with unilateral disease.Infiltration to other organs bone marrow being one the organ involved.Methodology: This study was conducted at Pakistan Institute Medical Sciences Islamabad for a period year.A total 47 known retinoblastoma were included in study.All underwent biopsy evaluation infiltration.Results: Out patients, 32 (68.1%) male and 15 (31.9%) female (ratio 2.13:1).37 (78.7%)patients...
We report a 49 year old male patient who presented with swelling in both thighs without pain and dyspnea. Platelet count was low (13,000/mm3) increased eosinophils (48.9%). Patient developed pulmonary embolism. His ADAMTS 13 level therefore diagnosed as TTP. Treatment given corticosteroid plasma exchange. After he lump the skull. Histopathology revealed vasculitis. Due to presence of vasculitis (TTP) along eosinophilia, finally case Churg Strauss Syndrome (CSS).
Objective: The objective of the study was to determine frequency appropriate use platelet concentrates in a tertiary care hospital. Material and Methods: It descriptive cross-sectional that conducted Department Pathology, Pakistan Atomic Energy Commission (PAEC) General Hospital, Islamabad for period six months from 1st January 30th June 2021. Patients both genders, above five years age receiving platelets transfusions during were included this study. An informed consent obtained patients....