Eugene P. Kennedy

ORCID: 0009-0008-7418-3774
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Tryptophan and brain disorders
  • Enzyme Catalysis and Immobilization
  • Glioma Diagnosis and Treatment
  • Bacterial Genetics and Biotechnology
  • Lipid Membrane Structure and Behavior
  • Metabolism and Genetic Disorders
  • Amino Acid Enzymes and Metabolism
  • Carbohydrate Chemistry and Synthesis
  • Pancreatitis Pathology and Treatment
  • Lipid metabolism and biosynthesis
  • Microbial Metabolic Engineering and Bioproduction
  • Esophageal and GI Pathology
  • Cancer-related cognitive impairment studies
  • Neuroendocrine Tumor Research Advances
  • Legume Nitrogen Fixing Symbiosis
  • Protein Structure and Dynamics
  • CAR-T cell therapy research
  • Cancer Research and Treatments
  • Glycosylation and Glycoproteins Research
  • Immunotherapy and Immune Responses
  • Enzyme Structure and Function
  • Enzyme function and inhibition

Carisma Therapeutics (United States)
2024-2025

NewLink Genetics (United States)
2015-2024

Louisiana State University
2024

Lumos Pharma (United States)
2020-2024

Indiana University – Purdue University Indianapolis
2024

Indiana University School of Medicine
2024

Urology of Virginia
2023

University of Virginia
2023

Thomas Jefferson University
2007-2020

Cedars-Sinai Medical Center
2020

10.1016/s0021-9258(19)50785-2 article EN cc-by Journal of Biological Chemistry 1956-09-01

10.1016/s0021-9258(18)71184-8 article EN cc-by Journal of Biological Chemistry 1954-12-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE ENZYMATIC SYNTHESIS OF TRIGLYCERIDESSamuel B. Weiss and Eugene P. KennedyCite this: J. Am. Chem. Soc. 1956, 78, 14, 3550Publication Date (Print):July 1, 1956Publication History Published online1 May 2002Published inissue 1 July 1956https://pubs.acs.org/doi/10.1021/ja01595a088https://doi.org/10.1021/ja01595a088research-articleACS PublicationsRequest reuse permissionsArticle Views347Altmetric-Citations223LEARN ABOUT THESE METRICSArticle Views are...

10.1021/ja01595a088 article EN Journal of the American Chemical Society 1956-07-01

10.1016/s0021-9258(18)69403-7 article EN cc-by Journal of Biological Chemistry 1960-05-01

10.1016/s0021-9258(18)69581-x article EN cc-by Journal of Biological Chemistry 1960-01-01

We introduce an intuitive particle-based model of time-symmetric quantum physics that gives a concrete description what goes on in the time between projective measurements system. The time-symmetry this means we ...Physical interpretations formulation mechanics, due to Aharonov, Bergmann, and Lebowitz are discussed terms weak values. most direct, yet somewhat naive, interpretation uses ...

10.1073/pnas.54.3.891 article EN Proceedings of the National Academy of Sciences 1965-09-01

10.1016/s0021-9258(18)91247-0 article EN cc-by Journal of Biological Chemistry 1964-06-01

10.1016/s0021-9258(18)70670-4 article EN cc-by Journal of Biological Chemistry 1957-10-01

10.1016/s0021-9258(18)71182-4 article EN cc-by Journal of Biological Chemistry 1954-12-01

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

10.1146/annurev.bi.26.070157.001003 article EN Annual Review of Biochemistry 1957-06-01

This paper describes the purification and some of properties an enzyme from human spleen that catalyzes hydrolysis sphingomyelin with formation ceramide phosphoryl choline.The enzyme, which is located in subcellular particulate fraction sediments between 700 8500 g, readily made soluble has been partially purified.Its pH optimum 4.5 5.0.It unaffected by divalent cations, chelating agents, sulfhydryl reagents, but inhibited phosphate.The attacks dihydrosphingomyelin, inactive toward...

10.1016/s0022-2275(20)40138-5 article EN cc-by Journal of Lipid Research 1967-05-01

Recent work has directed attention to the occurrence throughout nature of lipids in which long chain alkyl residues are linked glycerol by ether bonds, rather than more common ester linkages.The such bonds may be either cr,P-unsaturated (vinyl ether) type, as plasmalogens, or saturated.Analogues each types glycerophosphatides, and triglycerides, have been detected one fatty acid is replaced an linkage.This subject recently reviewed Hanahan Thompson (I).Among simplest batyl alcohol...

10.1016/s0021-9258(18)91137-3 article EN cc-by Journal of Biological Chemistry 1964-12-01

Indoleamine 2,3-dioxigenase 1 (IDO1) is the main enzyme that catalyzes first, rate-limiting step of so-called "kynurenine pathway", i.e., metabolic cascade converts essential amino acid L-tryptophan (Trp) into L-kynurenine (Kyn). IDO1, which expressed constitutively by some tissues and in an inducible manner specific subsets antigen-presenting cells, has been shown to play a role establishment maintenance peripheral tolerance. At least part, this reflects capacity IDO1 restrict...

10.4161/21624011.2014.957994 article EN OncoImmunology 2014-09-01

10.1016/s0021-9258(18)51844-5 article EN cc-by Journal of Biological Chemistry 1963-09-01

10.1016/s0021-9258(19)67968-8 article EN cc-by Journal of Biological Chemistry 1963-07-01

10.1016/s0021-9258(18)71383-5 article EN cc-by Journal of Biological Chemistry 1953-03-01

The cyclic (1 → 2)-β-D-glucans produced by species of Agrobacterium and Rhizobium resemble the membrane-derived oligosaccharides Escherichia coli in their periplasmic localization, intermediate size, 2)-β-D-glucan backbones. regulation biosynthesis tumefaciens is now shown to parallel osmotic oligosaccharide . This result suggests a general role for adaptation Gram-negative bacteria as ecologically diverse enteric soil bacteria.

10.1126/science.3941890 article EN Science 1986-01-03
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